You make it sound like it'll be very very scary or something along those lines, what?
Sorry, I half-typed a full explanation, but cut it to keep the post short and to the point.
Sometimes it worked fine. (According the SAN vendor it was supposed to, after all.) But when it didn't,
all the Windows VMs would crash/freeze. That was easy enough to deal with - select all and power cycle in the VM manager.
Linux VMs would keep running, but some random % of them would switch their storage mounts into read-only mode. Depending on what we were using the VM for, it might be hours, days, or weeks before we noticed an issue. You could use the mount/remount command to fix it, or just restart. We eventually configured monitors that triggered an alert if a file system was in read-only mode.
My point is just that "boot it into Linux and see if you still have the problem" isn't probably the best diagnostic, since a different OS may mask a failure, or respond in a completely different way than you might not realize has the same root cause.
My favorite weird-very-specific-storage-problem was a bad SATA cable on my home PC. Probably about 2010-ish. The only obvious symptom was that if I tried to launch Chrome, the system would freeze for about a minute solid, then carry on as if nothing happened. I put up with it for a while (I mostly used Firefox anyway) but eventually decided to poke around and see what the issue was. That was when much-younger-me learned about the Windows Event Viewer and how to use it to find storage errors.