This sounds good in theory, until they forget to point the remote during the whole macro sequence and something gets thrown off. I've heard it before... the receiver switches inputs but the TV doesn't, so they press it again and the TV will switch but then the reciever is 1 input ahead of where it should be and then I get a text that the "TV is broken because the sound isn't working". It's maddening
That is what the help button on a Logitech Harmony is for. This is how my AV calls with family go nowadays:
Them: "My TV won't work."
Me: "Did you hit the help button on the remote."
Them: "Ok, it is asking me ______"
Me: "Hit the yes button."
Them: "Now it is asking me _____"
Me: "Hit the no button."
Them: "Now it is asking me _____"
Me: "Hit the yes button."
Them: "Oh yay it works now!!!!"
Me: "Have a nice day."
That is like a 2 minute conversation instead of 30 minutes trying to get them to actually understand what is happening. And after a while some of them got the hang of going through the help menu themselves.
Now some equipment is harder to Harmonize than others, such as any TV without discrete inputs commands. Like in your example, optimally the TV and receiver will have a discrete commands for each input so even if they blast the same command twice the input stays the same. Any equipment that requires scrolling through inputs only will be a Harmony hack-a-thon that will fail on them eventually.
Which is why I demand to be let in on all their major electronic purchases, and I act like non-Harmonizable equipment will give you cancer. When in doubt, Samsung stuff always plays ball and people are comfy with that brand.
Oh and the other side is you have to NAIL the Harmony programing, and that can be a process. But it is worth it to hide all that modern complication without having to forgo the advantages of the equipment.