Karlitos,
I don't know if this is any help to you or not, but maybe it will give you something to compare to/eliminate -
My current setup is 2x MSI Lightning 7970s driving 5x NEC 2490WUXi's in Portrait mode.
2 via DVI and 3 via mini-DP to DVI Monoprice active adapters.
I run in either 6000 x1920 or 8000x2560 (with VSR turned on) both @60hz in both eyefinity and in std. Windows.
Prior to this I used 3x NEC 2490WUXi's in landscape mode @ 5760x1200 or 7680x1600 (with VSR on), again @ 60hz in both eyefinity and in std. Windows.
I have been using the MSI 7970 Lightnings and 3 monitors since about 6 months after MSI released them.
I just changed to the 5 monitor setup in the last week.
Windows does require the AMD driver to be installed before it will properly handle 3+ monitors in Windows (this is without eyefinity being enabled)
Most of my gameplay is the Borderlands series and the Darksiders series.
Nothing real stressful there.
I tried Fallout 4 and it doesn't exhibit any real display issues, but was never designed to use CF or MM, so it is a hack to get it to display well enough to see all the HUD stuff.
The most important part is I don't and haven't experienced any of the issues you have outlined (ever) and am currently using the 15.12 Crimson drivers, have steped incrementally with each new non-beta release.
My OS is Windows 2012R2, which is based on Windows 8.1.
Both cards are identical and are set for 1100/1600 under load and 500/1400 at idle on the primary card and the secondary card shuts down at idle (I leave ULPS active).
Maybe there are some clues/hope in this for you
I don't know if this is any help to you or not, but maybe it will give you something to compare to/eliminate -
My current setup is 2x MSI Lightning 7970s driving 5x NEC 2490WUXi's in Portrait mode.
2 via DVI and 3 via mini-DP to DVI Monoprice active adapters.
I run in either 6000 x1920 or 8000x2560 (with VSR turned on) both @60hz in both eyefinity and in std. Windows.
Prior to this I used 3x NEC 2490WUXi's in landscape mode @ 5760x1200 or 7680x1600 (with VSR on), again @ 60hz in both eyefinity and in std. Windows.
I have been using the MSI 7970 Lightnings and 3 monitors since about 6 months after MSI released them.
I just changed to the 5 monitor setup in the last week.
Windows does require the AMD driver to be installed before it will properly handle 3+ monitors in Windows (this is without eyefinity being enabled)
Most of my gameplay is the Borderlands series and the Darksiders series.
Nothing real stressful there.
I tried Fallout 4 and it doesn't exhibit any real display issues, but was never designed to use CF or MM, so it is a hack to get it to display well enough to see all the HUD stuff.
The most important part is I don't and haven't experienced any of the issues you have outlined (ever) and am currently using the 15.12 Crimson drivers, have steped incrementally with each new non-beta release.
My OS is Windows 2012R2, which is based on Windows 8.1.
Both cards are identical and are set for 1100/1600 under load and 500/1400 at idle on the primary card and the secondary card shuts down at idle (I leave ULPS active).
Maybe there are some clues/hope in this for you