ModestGamer you probably don't know my background, I was a process technology development engineer at Texas Instruments...worked on nodes spanning from 0.5um down to 32nm with continuing government grants and university affiliations (dual employment as adjunct professor at a local university as well as process development engineer at TI) working on sub-16nm technology extensions and it is my professional opinion that silicon is most certainly not dead nor is 22nm "nearing the end".
That's not just mantra in the form of "they always say Moore's law is dead and they are always wrong"...I'm speaking from having played a role in the development of the really cool stuff that hasn't even come to the forefront of the media's attention. And that really cool stuff has legs to run another 20yrs.
Without a doubt the limits of scaling are 100% economical. The materials science and basic physics is already at our disposal for continuing to shrink circuits for decades to come. And by "shrink" I mean increasing xtor density and electrical performance, but not the kind of 1-dimensional usage of the term as used by laymen where they think of the channel narrowing, etc.
When I see "scaling is dead" arguments, and they are popular so I see them often, I just think it is such a needlessly self-defeating perspective. But there is the big question mark regarding cost and whether enough consumers can be pooled together to buy products which will justify developing the shrink in the first place.
But that is true of virtually any product on the drawing board right now in any industry. Does the TAM justify the development expense? At TI we decided it no longer did at 32nm so we shut down R&D and went fabless for CMOS logic at 45nm and smaller. (kept the fabs for the still lucrative analog stuff)
One last thing, 5nm in the traditional node-scaling label schema is where currently known/identified scaling solutions are expected to lose steam. That's if we do nothing to expand the edge of the envelope between now and when 5nm is released to production.
What is being done between now and when 5nm is released to production is improving the integration and process technology so as to reduce manufacturing costs and increase the robustness of in-field product lifetime.
edit: This thread has all kinds of good stuff in it if you are interested in more reading.
And
this post from that thread definitely hits on stuff related to the OP of the current thread.
(and when you read the stuff in that thread keep in mind we only make the tip of the iceberg public information, the bulk of what is going on is never publicized for all the obvious competitive reasons...having seen and done some of the stuff that isn't public yet you'll just have to take my word for it when I say that shrinking is nowhere close to dead)