This is too general of a question for anyone to really help you, you'll need to be a little more specific if you want any information. Are you looking for ideas for a new build? What do you consider to be a "large" budget?
If you want to see what is out there in general, do a search for the build guides that various sites post every couple months. They generally start with budget, midrange and "extreme" systems and range from $1k-$3k. Other places like MaximumPC and LinusTechTips sometimes do "extreme" builds or "dream machines" if you just want to see what's ridiculous. Otherwise I can't really help you without more info.
Here is what I'm looking at this month:
Intel i7-4770k
Asus Maximus VI formula
Cooler Master Glacer 240L
Corsair AX1200i
Corsair Vengeance Pro 16-32gb 1866
Corsair 750d
EVGA GTX 780 or 780ti x2
Samsung 840 pro 256gb SSD x2
WD black 2TB HDD
QNIX QX2710 1440p OCed to 120hz
Noctua Fans
That's totals up to around $4k but doesn't include some of the extras like an Individually Sleeved Cable kit, the 24AWG cable, a new WASD keyboard, a Fnatic Sensei mouse, etc. I'm still up in the air on a couple of the minor things like case fans (I hate the look of the Noctua fans but the performance is amazing). I primarily game, but I also do some video editing/encoding and software development.