My experience was that their drivers were actually fairly flawless for me - and that was with a lot of early day Vista handling. Not a single hiccup even though this system had to serve as a testbench for several cards, never needed to uninstall/fix drivers or CCC. And my drivers never lost any settings either *cough, cough*What Communism wrote, who appears to be a Crossfire user, is not really unlike the typical AMD experience. However, most people ignore the small details and it doesn't bother them.
AMD drivers as a whole work pretty well, with little to be bothered with, however, AMD drivers have little annoying problems all the time. Those small issues which he mentioned would not bother most people, so you don't really see a large flood of people complaining, but these problems do exist.
I'm sure there are issues that I simply managed to avoid, but in all honesty I think that few people trip over the same issues that you guys found. Especially if you stay out of Crossfire woes (neither CF nor SLI strikes me as something desirable).