He, I have an Abit KN8 Ultra NForce 4 mobo and have ran 4xRAID 0 with 4 Seagate 80GB Sata II 7200.9 drives. It was fast as heck, sandra did 205MB/s write to them and HDTach did over 350MB/s read. Games have never loaded faster for me, windows installed in 9 minutes. Booted up insane. I would recomend it highly!!!!
But yes, there are downsides, you do have a 4 times higher risk of HDD failure. But to be honest, and I can say this because I have a storage server to hold all my important data, I don't care if my raid hiccuped and I would have to reinstall windows. Personally I think the performance outweighs the negatives.
It all comes down to what you want, if you want just raw speed, get 4 of those seagates, they are $51 a piece on newegg right now and are fast as heck. But if don't like the possibilty of losing data then it's not for you. However the mobo I have supports, RAID 0, 1, 0+1 5 and Spanning. I run Raid 5 ATM, because I've been testing out the different raids, and however the write speeds aren't as great as them all in Raid 0, the read speeds are very similar. Plus the Abit KN8 Ultra supports hot swap sata. Which is a plus since you can swap hdd's out while it's running in a Raid 1 or 5 situation.
But if you do have questions let me know, I'd be happy to answer.
Rob