I'd recommend you ween yourself off of any motherboard utility, as most of the stuff you can do right in the UEFI:
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They usually cause more headaches than help.
I agree with that. Completely.
You can "uninstall" the ASUS Suite software, but it will still leave some remnant programs which load at boot-time. They do not "do anything" -- as much to say they don't use any clock-cycles. They just use a tiny bit more of your memory -- unnecessarily. The only way to get rid of them requires use of an ASUS utility. I would run a search at the ROG web-pages.
My Sabertooth Z170 board is listed in my sig. The Suite version bundled with the board was really elegant, and assisted me with tuning my fans and other features, but I wish I hadn't installed it for the troubles I mentioned here already.
And the advantage of ASUS boards which I cannot guarantee exist for those of other board-makers: you can set up the fans and "fan-curves" in BIOS. So you don't need the Suite software. Even the monitoring feature is totally unnecessary. You're better off using HWInfo64 or HWMonitor.
I don't think there are many serious overclockers who rely on board-makers' windows programs, either. I don't.