Just a few things of note. First of all, whoever said that PS/2 connections are faster were lying. I'm sorry to say that I don't remember the numbers off the top of my head, but I can tell you that when I switched from PS/2 to USB, I actually noticed the difference (the same could not be said for switching from an Athlon 2000+ to a 2200+). It's quite nice. Secondly, I've gotta be honest, I would not even consider anything but an optical mouse. I've never used this boomslang, but I don't see how it could possibly be better than what I have. Thirdly, I would recommend either the Ratpadz Mouse Pad or the OCZ (I don't remember the product name) mouse pad. The Ratpad is the best surface that I have used, but I had to get rid of it because it was too small. The OCZ is what I use now, and while it doesn't have the wonderful surface of the Ratpadz, it's absolutely wonderful to be able to move my mouse as much as I want to with little trouble. Fourth, as for picking up, I have had no problems picking them up without moving the screen. Finally, I'll put my vote in for the Microsoft Intellimouse 3.0, with an admission of some bias. I'm 6'9" and I have HUGE hands. I actually find these wonderful mice to be a little small, but they are MUCH larger than other mice I've used. I may hate Microsoft like the plague, but I not only have one of these mice at home, I PAID for one for the office because they're so incredibly easy to use. I'll say this: I'll never go back. IMO, Logitechs are not onl way too small, but they just always seem cheaply made. I SAID SEEM!! I didn't say that they were, but since I was 13 playing on my first computer and the mouse went out and was replaced by a Logitech, I can honestly say that I will never buy one again. They weight about half an ounce and just feel like they could be crushed in my hand. Totally personal opinion, but I wanted to at least mention it.