Californication Season 1 was awesome. Not exactly a spoiler but the first season can be viewed as self-contained mini-series, where the season finale could have very well been a series finale. So even if you don't love it, you only have to invest in 12 episodes and you still get closure.
Season 2 was also good but not quite as great. Season 3 has felt like one big jump over the shark, continually trying to be more outrageous, revolting, unbelievable and explicit. The new characters that were introduced just can't compete with the great Lew Ashby from Season 2.
Weeds, I think, suffered a similar fate. It sucks you in in the first 3 seasons, the 4th was kind of interesting but you just know it's starting its downward spiral. The 5th season was just plain annoying and the lead character that you once loved just becomes a weak, annoying bitch. I honestly don't care about Season 6 (due next year).
I need to start watching Dexter. Saw some clips from Entourage here and there and I think that might also be an interesting show. What does ATOT think? Dexter, Entourage...or both?
I'd take that about Californication even further. You can watch just the last episode of the first season and you'll get everything that show has to offer. Its not a bad show, but they're not going to top that episode for impact on the viewer. Most of the episodes preceding it didn't even add that much (and I think that episode recounted what did anyways).
Dexter was stellar the first season, but now (ok season 2 and 3, haven't seen any of the newest one) feels similar to most other shows. The first one had this tension and creepiness to it that almost made you not want to watch, but you stayed glued to it.
Weeds was pretty entertaining the first season, but it really falls off, and there's too much junk to get the good parts in the later seasons.
The couple of episodes of United States of Tara were pretty good.
If you have Netflix, I recommend checking out season 1 of Party Down. It was on Stars.
There was another show I watched in the background on Netflix, not sure where it was aired. Its called Satisfaction, and is about a brothel. Was decent. It had about as much nudity/sex as Californication, but focused on several different characters.