Can human-sex be transplanted ? :O

[elpres05]

Just wondering if this is even possible by 1%

and if it is... would probably be the best medical inventions of all time.

Or maybe a hybrid system that can reproduce on its own ?

 

[bendixG15]

Keep wondering ....

 

[elpres05]

Originally posted by: bendixG15
Keep wondering ....

Okay...

 

[Gibsons]

I don't understand the question.

 

[elpres05]

Originally posted by: Gibsons
I don't understand the question.

You do know the fundamental difference betweem a man and a women, don't you?

Technically, If you are to be called a women/girl, what must be changed.......

 

[JHutch]

I think he means:

Can the human sexual reproductive system be transplanted/replaced by a completely new system (i.e., replace a man's reproductive system with a woman's)?

Answer: No. Some parts can be replaced, but to get a functional whole that can mate and reproduce, no. (At least, not currently or in the foreseeable near future)

 

[f95toli]

The idea has been discussed. The problem with a "transplant" is that you (usually) still have either a set of XY or XX chromosomes and no form of surgery can change that . Hence, only changing the "plumbing" won't be enough.
That said, an artitificiall "womb" might eventually become possible and if you combine this with "gene splicing" (or whatever the technical term is) it might eventually become possible for two men or two women to have a child together.

 

[elpres05]

Originally posted by: f95toli
The idea has been discussed. The problem with a "transplant" is that you (usually) still have either a set of XY or XX chromosomes and no form of surgery can change that . Hence, only changing the "plumbing" won't be enough.
That said, an artitificiall "womb" might eventually become possible and if you combine this with "gene splicing" (or whatever the technical term is) it might eventually become possible for two men or two women to have a child together.

and what about a hybrid system ?

What if one body has all the sparkling features, a hybrid system, reproduction on will.

 

[forrestroche]

Originally posted by: elpres05

Originally posted by: f95toli
The idea has been discussed. The problem with a "transplant" is that you (usually) still have either a set of XY or XX chromosomes and no form of surgery can change that . Hence, only changing the "plumbing" won't be enough.
That said, an artitificiall "womb" might eventually become possible and if you combine this with "gene splicing" (or whatever the technical term is) it might eventually become possible for two men or two women to have a child together.

and what about a hybrid system ?

What if one body has all the sparkling features, a hybrid system, reproduction on will.

My guess is hybrid system would be more complicated. But the other posters I suspect are talking out their collective smelly holes. None of them has given a convincing reason that it can't be done (the transplant). If the donor was compatible (a twin sibling would be ideal), why not? The chomosome thing has nothing to do with organ rejection. I think it would work.

Picture it: Your twin sister dies in a horrible accident, leaving only her reproductive organs intact (I will leave it to others to describe this accident in greater detail). Her uterus, vagina, etc. are rushed to the hospital where transplant specialists have already removed your penis and are using a chisel to widen your pelvis-hole (that's the technical term for it). They stuff in the new hardware, hook up blood vessels and (of course) the urethra, shoot you full of hormones, and voila! After a year of physical therapy, constant injections, and round-the-clock counseling (after all, your sis is dead, you scavenged her parts like she was an old subaru, and now you're now a woman) - after all that, now you're ready to find a boyfriend and have a kid! It sounds not only possible, but if you pitch it as a reality one-off to the right producer, I bet you can get it financed tomorrow.

Just my two cents.

 

[elpres05]

forrestroche, i think you missed the part of hotrod over the archeological dig

 

[Gibsons]

Originally posted by: forrestroche

Originally posted by: elpres05

Originally posted by: f95toli
The idea has been discussed. The problem with a "transplant" is that you (usually) still have either a set of XY or XX chromosomes and no form of surgery can change that . Hence, only changing the "plumbing" won't be enough.
That said, an artitificiall "womb" might eventually become possible and if you combine this with "gene splicing" (or whatever the technical term is) it might eventually become possible for two men or two women to have a child together.

and what about a hybrid system ?

What if one body has all the sparkling features, a hybrid system, reproduction on will.

My guess is hybrid system would be more complicated. But the other posters I suspect are talking out their collective smelly holes. None of them has given a convincing reason that it can't be done (the transplant). If the donor was compatible (a twin sibling would be ideal), why not? The chomosome thing has nothing to do with organ rejection. I think it would work.

Picture it: Your twin sister dies in a horrible accident, leaving only her reproductive organs intact (I will leave it to others to describe this accident in greater detail). Her uterus, vagina, etc. are rushed to the hospital where transplant specialists have already removed your penis and are using a chisel to widen your pelvis-hole (that's the technical term for it). They stuff in the new hardware, hook up blood vessels and (of course) the urethra, shoot you full of hormones, and voila! After a year of physical therapy, constant injections, and round-the-clock counseling (after all, your sis is dead, you scavenged her parts like she was an old subaru, and now you're now a woman) - after all that, now you're ready to find a boyfriend and have a kid! It sounds not only possible, but if you pitch it as a reality one-off to the right producer, I bet you can get it financed tomorrow.

Just my two cents.

Quite another matter to get the ovaries working properly I suspect.

 

[forrestroche]

Originally posted by: Gibsons
Quite another matter to get the ovaries working properly I suspect.

Well, I just spent the last day checking into THAT, and I think we can get it done. These reality shows have decent budgets and access to doctors looking to make a name.

Let me make a few more calls...

 

[DrPizza]

Originally posted by: Gibsons

Originally posted by: forrestroche

Originally posted by: elpres05

Originally posted by: f95toli
The idea has been discussed. The problem with a "transplant" is that you (usually) still have either a set of XY or XX chromosomes and no form of surgery can change that . Hence, only changing the "plumbing" won't be enough.
That said, an artitificiall "womb" might eventually become possible and if you combine this with "gene splicing" (or whatever the technical term is) it might eventually become possible for two men or two women to have a child together.

and what about a hybrid system ?

What if one body has all the sparkling features, a hybrid system, reproduction on will.

My guess is hybrid system would be more complicated. But the other posters I suspect are talking out their collective smelly holes. None of them has given a convincing reason that it can't be done (the transplant). If the donor was compatible (a twin sibling would be ideal), why not? The chomosome thing has nothing to do with organ rejection. I think it would work.

Picture it: Your twin sister dies in a horrible accident, leaving only her reproductive organs intact (I will leave it to others to describe this accident in greater detail). Her uterus, vagina, etc. are rushed to the hospital where transplant specialists have already removed your penis and are using a chisel to widen your pelvis-hole (that's the technical term for it). They stuff in the new hardware, hook up blood vessels and (of course) the urethra, shoot you full of hormones, and voila! After a year of physical therapy, constant injections, and round-the-clock counseling (after all, your sis is dead, you scavenged her parts like she was an old subaru, and now you're now a woman) - after all that, now you're ready to find a boyfriend and have a kid! It sounds not only possible, but if you pitch it as a reality one-off to the right producer, I bet you can get it financed tomorrow.

Just my two cents.

Quite another matter to get the ovaries working properly I suspect.

Why's that?

 

[patentman]

Originally posted by: forrestroche

Originally posted by: elpres05

Originally posted by: f95toli
The idea has been discussed. The problem with a "transplant" is that you (usually) still have either a set of XY or XX chromosomes and no form of surgery can change that . Hence, only changing the "plumbing" won't be enough.
That said, an artitificiall "womb" might eventually become possible and if you combine this with "gene splicing" (or whatever the technical term is) it might eventually become possible for two men or two women to have a child together.

and what about a hybrid system ?

What if one body has all the sparkling features, a hybrid system, reproduction on will.

My guess is hybrid system would be more complicated. But the other posters I suspect are talking out their collective smelly holes. None of them has given a convincing reason that it can't be done (the transplant). If the donor was compatible (a twin sibling would be ideal), why not? The chomosome thing has nothing to do with organ rejection. I think it would work.

Picture it: Your twin sister dies in a horrible accident, leaving only her reproductive organs intact (I will leave it to others to describe this accident in greater detail). Her uterus, vagina, etc. are rushed to the hospital where transplant specialists have already removed your penis and are using a chisel to widen your pelvis-hole (that's the technical term for it). They stuff in the new hardware, hook up blood vessels and (of course) the urethra, shoot you full of hormones, and voila! After a year of physical therapy, constant injections, and round-the-clock counseling (after all, your sis is dead, you scavenged her parts like she was an old subaru, and now you're now a woman) - after all that, now you're ready to find a boyfriend and have a kid! It sounds not only possible, but if you pitch it as a reality one-off to the right producer, I bet you can get it financed tomorrow.

Just my two cents.

While I don't disagree that you could transplant the "hardware" so to speak, men simply aren;t programmed to produce the same hormones as women, and even if they do, they don;t produce them in the correct amounts naturally. Reproduction requires a ridiculous amount of hormonal regularion that is not performed by the female reproductive organs. So I think that while the transplant could be done and you could look like a woman, you would probably be sterile.

Moreover, why in the hell would anyone want to do this? Sex is just about the only fun thing left on earth that is almost 100% natural. Only people I can see wanting to do this would be guys who are too socially inept to go out and find a woman.

 

[elpres05]

LoL @ your natural fun theories

 

[wwswimming]

in 1988 i taught a CAD class with about 6 students in Silicon Valley. one of the participants
was about 6'4" and wore a dress. i liked them, no not romantically, just enjoyed having
them in the class ... she was genuinely interested in the subject, 3D modelling. very
big-boned - no pun intended, God it's hard to resist wisecracks ... pretty definitely a
guy in a dress. i don't know where she was relative to the timing of the surgery.

reminded me of the movie, "the world according to Garp". wasn't there a transgender
person in there ?

it seems like an awful lot of trouble to go to. i don't understand the feelings & the
motivations. but mutual respect was-is a good way to go.

still, undeniably, there is a "giggle factor".

 

[Gibsons]

Originally posted by: DrPizza

Originally posted by: Gibsons


Quite another matter to get the ovaries working properly I suspect.

Why's that?

Oogenesis is something we don't understand all that well. Currently when we artificially induce ovulation, it's sort of like making your car go by ramming a train into it. Okay, really bad analogy, but our current methods seem pretty crude to me. Fertility drugs frequently causing multiple births (quintuplets, etc) as an example. So, you place some ovaries in a male, you can keep them alive, I suspect, with lots of hormone inections. But getting them ovulate properly might prove to be more delicate (not just in hormones, but maybe some other things we don't even know about yet) than we're capable of at this point. Just IMO of course.

 

[PlasmaBomb]

Originally posted by: forrestroche

My guess is hybrid system would be more complicated. But the other posters I suspect are talking out their collective smelly holes. None of them has given a convincing reason that it can't be done (the transplant). If the donor was compatible (a twin sibling would be ideal), why not? The chomosome thing has nothing to do with organ rejection. I think it would work.

Picture it: Your twin sister dies in a horrible accident, leaving only her reproductive organs intact (I will leave it to others to describe this accident in greater detail). Her uterus, vagina, etc. are rushed to the hospital where transplant specialists have already removed your penis and are using a chisel to widen your pelvis-hole (that's the technical term for it). They stuff in the new hardware, hook up blood vessels and (of course) the urethra, shoot you full of hormones, and voila! After a year of physical therapy, constant injections, and round-the-clock counseling (after all, your sis is dead, you scavenged her parts like she was an old subaru, and now you're now a woman) - after all that, now you're ready to find a boyfriend and have a kid! It sounds not only possible, but if you pitch it as a reality one-off to the right producer, I bet you can get it financed tomorrow.

Just my two cents.

Problem 1) If your twin is female and you are male you aren't identical twins, therefore there is no guarantee that you would be compatible, it really depends on your parents genotypes.

Problem 2) Hooking up a nerve supply ... can't currently be done to my knowledge

Problem 3) Altering the pelvic girdle, a females? pelvic girdle is wider and shallower than a males?, hacking away at a males to make it wider would probably result in a fragile pelvis due to the loading not being properly distributed. Also I'm not sure the male symphysis pubis would be able to flex to facilitate child birth.

Your pelvis-hole (that's the technical term for it)

 

[Dr. Jessica]

Oogenesis is something we don't understand all that well. Currently when we artificially induce ovulation, it's sort of like making your car go by ramming a train into it. Okay, really bad analogy, but our current methods seem pretty crude to me. Fertility drugs frequently causing multiple births (quintuplets, etc) as an example. So, you place some ovaries in a male, you can keep them alive, I suspect, with lots of hormone inections. But getting them ovulate properly might prove to be more delicate (not just in hormones, but maybe some other things we don't even know about yet) than we're capable of at this point. Just IMO of course.

That,s a good point, but, the ovaries produce estrogen and would keep the body in supply. Which would allow the brain chemistry to alter, to a point, making the body adapt to the new jobs it needs to do.

As for someone saying that nerves would not be able to be put back together; in some cases nerves have been known to connect to new tissue and create nerve clusters if treated correctly. That is just what I have read.

 

[wirednuts]

i always wondered if you have that surgery that turns your penis inside out into a vagina, does it get wet?

 

[Ninjahedge]

Viral supplantation.

You would need to find a way to graft the proper genes into every cell of the person or you run the risk of hormonal imbalance, immunilogical response, or just plain sterility.


BTW, a male/female twin is not a "twin". It is two seperate gene structures that were conceived and born at the same time. You can't just take an ovary out and think it was 99% the same except for the X/Y gene.....

 

[piasabird]

Crockadile Dundee movie had a transgender He-she-la. So he was out at a bar once and he resorted to a Grab-Check.

Even the bone structure is different in a man and a woman. So the differences are a lot deeper than you might think.

Maybe one day you can just put some nanites into a pill and just swallow them and they will within a week or two be able to change your sex and your genetic structure. It is more likely there might be able to be a clone you could move your mental ability into. Think about the show Kyle XY. 18 years to grow a clone.

 

[lord_emperor]

We all know that reproduction is of secondary concern, the #1 question is can the recipient experience the appropriate orgasm?

 

[jhu]

It's technically possible. However, it's not currently possible with our level of technology. So here's how it would be done properly:

Method 1:

For men:
1) Ovaries need to be grown from the man's own cells and then implanted. This prevents rejection from implanting someone else's ovaries. The stem cell that the ovary is grown from would need to have its Y chromosome removed and an X chromosome added. So that other X chromosome would have to come from the man's father.
2) A uterus would need to be grown as well. This can be from the same stem cell(s) that produced the ovaries.
3) Surgical alterations plus implantation of grown organs.

For women:
1) Make testes and other support organs (epididymis, prostate, etc.) from stem cells with X chromosome replaced by father's Y chromosome.
2) surgical alterations plus implantation of grown organs.

Method 2:
For men:
1) Grow a brainless female body with man's stem cells. Stem cell would have the second X chromosome from the father. It would also lack a Y chromosome. Once the brainless body is grown, transplant man's brain into female body.

For women:
2) Same as for men, but make a man's body instead and get the Y chromosome from the father.

And there you go: a proper sex change that's not just appearances.

 

[William Gaatjes]

I would place my bets on Gibsons and Patentman.

IMHO:
The different hormones produced must be at the right amounts , for the right time and at the right time. The biological clock which is synchronized to the earth/sun/moon cycle, i suspect it to be a bit different between men and women. Because of the different hormone structure. We also have to remember that some genes creating male or female tissues are activated only once. And only when at the right moment during the growth of the fetus (?) the right amount or combination of hormones are present to activate that specific gene that is needed only once for a specific tissue. Epigenetics claims that the body is very dependent on the chemicals in the environment(which may emulate the function of hormones). Epigenetics also claims that the time duration that genes are active are dependent on the environment.
But this is because the human body uses multiple hormones to activate multiple genes at the same time to activate the "locked down" genes. The ones that can make significant and possible lethal changes.

Intermezzo :
Why use multiple genes at the same time ? Because then you do not need that many genes to become more complex. You just reuse your existing genes as much as possible. Evolutionary this makes sense. It is easier to copy then to create from scratch. The "from scratch" system is really just a virus that adds some new dna in the existing genome of some form of life. Where did the virus get it from ? Well, all the time because of the noisy EM spectrum we are surrounded with, energy levels of atoms are always a bit changing. This causes for the random creation of different biological chemicals that will eventually be new dna. From gene to amino acid. From amino acid to protein. Most combinations of atoms also known as proteins are not useful. These need to much energy to be useful or are too unstable meaning requiring to less energy. Analogy : The electromechanical spring unloads not at all or the electromechanical spring unloads to easy.
But some are useful.
End intermezzo :

You can indeed flush a body with a mixture of hormones, but the special tissues are just not there. It is not just a bunch of ovaries and a womb. If i am not mistaken, the brainstem and the limbic system are wired slightly different to take care of all the biological timings. Part of the human brain is just a state machine that functions on the right amount of hormones at the right time. After that, the entire body is build differently, more gentle. But this is just because of the hormone levels that are present. Think of female body builders and women after menopause. The first example becomes more masculine because of the high levels of male hormones. The latter becomes less feminine (also in behavior) because of the decrease of female hormones.