Sound like the answer is more of a “NO” then a yes!u can do anything with a proper dremel, and threaded metric taps so you can tap new holes to install standoff's where needed :T
The dremel will be needed to cut out the rear IO incase they dont allign, which i doubt they will, and the taps to put standoff's where needed.
WELL ...
its more like how far you're willing to have fun.
Ive seen lot of people retrofit old mac pro's into customs and do a excellent job.
Its just, are you going to do it for fun? or to save budget on a case?
If its fun, time and cost are moot.
If its budget... well, there are better things to do to save those extra dollars.
It depends most motherboards have standard standoffs designed for ATX, MATX, Mini ITX etc. Not every hole has to match. If a few mounting positions match, then you can try some older plastic standoffs. That was common in the past. Just take the motherboard out and lightly hold it in any standard case and see if any mounting points match up.
Example: https://www.amazon.com/Aexit-Spacer...=8-6&keywords=aexit+motherboard+nylon+support
You really only need about 4 standoffs / screws to be in place. Not all of them need to be installed. It's not like the board is under any stress lol.
I was wonder for a possible future install project if some of these cases might make installing a Lenovo ThinkCentre or ThinkStation sff motherboard possible? I would love just the components including the proprietary motherboard to a nicer, more roomer case with full size graphics card room, etc...