put it as far away from you as possible.
be careful with your HSF choice, i have a ThermalTake D-Orb 3 LowNoise and will NOT be reccomending it to anyone, although i havent really been able to compare it with anything.
i can however vouch for SG Barracuda IV HDD, never heard any noise from it at all. tho i proly wouldnt hear it over the damned HSF anyway.
fans and CD-Drives (and old HDD's) make most noise, so always make those selections carefully.
other reccomendation would be to make sure all youre parts are screwed in tightly, and the case cover is on securely.