Covidiots thread

[blackangst1]

Who is the largest veterinary medication producer in the USA?

Zoetis

Who owns the company?

Pfizer

Well, until they spun it off.

So I guess conservatives are sticking it to Pfizer and their vaccine by buying horse medication from their former subsidiary that's now owned by wall street institutions?

Yeah, stick it to The Man!

Ivermectin is a horse medication? Might want to inform WHO. They consider it one of the most important human drugs for humans. Quit spreading lies.

 

[blackangst1]

Dumbass!

So convincing!

 

[blackangst1]

They are hosting the articles. They don't publish and peer review. You are posting review articles, not primary research, written by the people selling ivm.

You are asking me to research, but I'm just reading your links lol.

How about listening to the American Medical Association?

Why ivermectin should not be used to prevent or treat COVID-19

How about listening to WHO?

 

[Lanyap]

Which brings up the question why would someone take IVR over the vaccine? Easy answer. IVR is one of the most important and safest drugs available, with many human uses (see my WHO link above). Its been used off-label for many things successfully, now including covid (Ive already provided several links of double blind studies. If you want more, look yourself. Info is out there). The science of treating illnesses is all about off-label prescripting. Which IVR is. So...the choice is, take an off-label drug that so far clinically has shown promise and has been safely used in humans for 10+ years, , or take a vax less than 2 years old with no history. Thats the choice. Theres a reason so many medical professionals are refusing the vaccine.

You have really gone over the line of COVID mis-information. If this was FB, Twitter, etc. your account would be suspended with all the bullshit you're spewing.

From your WHO link. WHO recommends ivermectin for parasitic type infestations. Nothing here about COVID.

eEML - Electronic Essential Medicines List

list.essentialmeds.org

Ivermectin

Essential medicine status
General description
Ivermectin is a antiparasitic medicine with a broad spectrum of activity. It is used in the treatment of onchocerciasis (river blindness), strongyloidiasis and other diseases caused by soil transmitted helminthiasis. It is also used to treat scabies.
INN
Ivermectin
Medicine type
Chemical agent
EML status history
First added in 1987 (TRS 770) for Onchocerciasis
Added in 2011 (TRS 965) for Lymphatic filariasis
Added in 2017 (TRS 1006) for Strongyloidiasis
Added in 2017 (TRS 1006) for Trichuriasis
Added in 2017 (TRS 1006) for Ascariasis
Added in 2017 (TRS 1006) for Ancylostomiasis
Added in 2017 (TRS 1006) for Hookworm diseases
Added in 2019 (TRS 1021) for Scabies
Wikipedia
Ivermectin
DrugBank
Ivermectin

wiki. Parasitic type infections.

Ivermectin - Wikipedia

en.wikipedia.org

Ivermectin is a medication used to treat parasite infestations.[6][7] In humans, these include head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis.[6][8][9][10] In veterinary medicine, it is used to prevent and treat heartworm and acariasis, among other indications.[9] It can be taken by mouth or applied to the skin for external infestations.[6][11] It belongs to the avermectin family of medications.[6] It works through many mechanisms of action that result in death of the targeted parasites.[6]

Ivermectin was discovered in 1975 and came into medical use in 1981.[12][13] In 2015, William Campbell and Satoshi Ōmura won the Nobel Prize in Physiology or Medicine for its discovery and applications.[14] It is on the World Health Organization's List of Essential Medicines.[15] Ivermectin is FDA-approved as an antiparasitic agent.[16] In 2018, it was the 420th most commonly prescribed medication in the United States, with more than one hundred thousand prescriptions.[17] The medication is also being researched as a way to treat or prevent tropical diseases including yellow fever and malaria.

During the COVID-19 pandemic, misinformation has been widely spread claiming that ivermectin is beneficial for treating and preventing COVID-19.[18][19] Such claims are not backed by credible scientific evidence.[20][21] Research into its use is ongoing, and multiple major health organizations, including the U.S. Food and Drug Administration, U.S. Centers for Disease Control, and the World Health Organization have issued statements stating that ivermectin is not authorized or approved to treat COVID-19.

From one of your nih links. Wow, 72 patients in Dhaka, Bangladesh.

Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19

In 2015, the Nobel Committee for Physiology or Medicine, in its only award for treatments of infectious diseases since six decades prior, honoured the discovery of ivermectin (IVM), a multifaceted drug deployed against some of the world’s most ...

www.ncbi.nlm.nih.gov

The trial included 72 hospitalized patients in Dhaka, Bangladesh, who were assigned to one of three groups:

 

[Lanyap]

How about listening to WHO?

I know you're just fuckin with us now but where does WHO recommend taking ivermectin for COVID? It only recommends it for parasitic type infestations.

 

[blackangst1]

You have really gone over the line of COVID mis-information. If this was FB, Twitter, etc. your account would be suspended with all the bullshit you're spewing.

From your WHO link. WHO recommends ivermectin for parasitic type infestations. Nothing here about COVID.

eEML - Electronic Essential Medicines List

list.essentialmeds.org

wiki. Parasitic type infections.

Ivermectin - Wikipedia

en.wikipedia.org

From one of your nih links. Wow, 72 patients in Dhaka, Bangladesh.

Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19

In 2015, the Nobel Committee for Physiology or Medicine, in its only award for treatments of infectious diseases since six decades prior, honoured the discovery of ivermectin (IVM), a multifaceted drug deployed against some of the world’s most ...

www.ncbi.nlm.nih.gov

So irrelevant? You've never heard of of off label prescriptions? Im on two, at the moment.

We believe that the evidence to date supports the worldwide extension of IVM treatments for COVID-19, complementary to immunizations. The indicated biological mechanism of IVM, competitive binding with SARS-CoV-2 spike protein, is likely non-epitope specific, as reviewed [8], possibly yielding full efficacy against emerging viral mutant strains. IVM has been safely used in 3.7 billion doses since 1987, well tolerated even at much greater than standard doses [34,35] and used without serious AEs in the three high-dose COVID-19 treatment studies noted above [34,36,37]. In the current international emergency of COVID-19, with mutant viral strains, vaccination refusals and potentially waning immunities over months presenting new challenges, IVM can be an effective component of the mix of therapeutics deployed against this pandemic.




During the year since IVM treatment was first applied to COVID-19, another global scourge [5], results from more than 20 randomized clinical trials (RCTs) of IVM treatment of COVID-19 have been reported [2,6,7], with inpatient and outpatient treatments of COVID-19 conducted in 25 countries [2]. A likely biological mechanism has been indicated to be competitive binding with SARS-CoV-2 spike protein sites, as reviewed [8,9].


Yeah no science here folks.

 

[blackangst1]

I know you're just fuckin with us now but where does WHO recommend taking ivermectin for COVID? It only recommends it for parasitic type infestations.

I wasnt stating that. I was addressing the fact many say its for livestock only, when in fact its been used in humans quite a bit. Follow along sparky.

 

[brandonbull]

IIRC Rogan started the whole ivermectin craze by featuring that crazy doc on his show.

What kind of quack would recommend horse dewormer medication to humans?

Overseas Refugee Health Guidance | Immigrant and Refugee Health | CDC

Guidelines for the overseas medical examination for newly arriving US-bound refugees.

www.cdc.gov

 

[IronWing]

What kind of quack would recommend horse dewormer medication to humans?

Overseas Refugee Health Guidance | Immigrant and Refugee Health | CDC

Guidelines for the overseas medical examination for newly arriving US-bound refugees.

www.cdc.gov

See the two responses directly above your dishonest post.
Oh, and fuck off, traitor.

 

[VW MAN]

So convincing!

Yes you are absolutely 100% dumbass!

 

[Bitek]

Ivermectin is a horse medication? Might want to inform WHO. They consider it one of the most important human drugs for humans. Quit spreading lies.

The WHO recommends AGAINST using the drug for covid. As does CDC, as does AMA, as does FDA.

Therapeutics and COVID-19: living guideline

Updated 14 July 2022

www.who.int

"We recommend not to use ivermectin in patients with COVID-19 except in the context of a clinical trial.

Remark: This recommendation applies to patients with any disease severity and any duration of symptoms.

A recommendation to only use a drug in the setting of clinical trials is appropriate when there is very low certainty evidence and future research has a large potential for reducing uncertainty about the effects of the intervention and for doing so at reasonable cost."


MEANWHILE:

Head lice are having a rough go at in Florida tho. Bravo.

 

[Bitek]

So irrelevant? You've never heard of of off label prescriptions? Im on two, at the moment.

We believe that the evidence to date supports the worldwide extension of IVM treatments for COVID-19, complementary to immunizations. The indicated biological mechanism of IVM, competitive binding with SARS-CoV-2 spike protein, is likely non-epitope specific, as reviewed [8], possibly yielding full efficacy against emerging viral mutant strains. IVM has been safely used in 3.7 billion doses since 1987, well tolerated even at much greater than standard doses [34,35] and used without serious AEs in the three high-dose COVID-19 treatment studies noted above [34,36,37]. In the current international emergency of COVID-19, with mutant viral strains, vaccination refusals and potentially waning immunities over months presenting new challenges, IVM can be an effective component of the mix of therapeutics deployed against this pandemic.




During the year since IVM treatment was first applied to COVID-19, another global scourge [5], results from more than 20 randomized clinical trials (RCTs) of IVM treatment of COVID-19 have been reported [2,6,7], with inpatient and outpatient treatments of COVID-19 conducted in 25 countries [2]. A likely biological mechanism has been indicated to be competitive binding with SARS-CoV-2 spike protein sites , as reviewed [8,9].


Yeah no science here folks.

This is from that same crap review article.

They *think* maybe it binds to "spike protein sites"

The drug is not listed as an an anti viral.

Where does it bind? To the RBD then? Or somewhere else? How? Any structural modeling to show that?

The virus is studded with these. What's the effective dose?
Where's the clinical data? Where's the safety data showing is safe at that dose?

Where's the in vitro studies?

The author and IVM salesmen complain that the Peruvian president cut off the drug 10 mos ago, why aren't they getting the data to prove it? All they've got to show for it since then is a poorly written review paper?

What are the pharmas waiting for? They can do these studies easy enough. Where's their publications?

 

[MtnMan]

They are hosting the articles. They don't publish and peer review. You are posting review articles, not primary research, written by the people selling ivm.

You are asking me to research, but I'm just reading your links lol.

How about listening to the American Medical Association?

Why ivermectin should not be used to prevent or treat COVID-19

An exercise in futility...

Trying to change a trumpanzee's mind by using verifiable facts. No matter how many times you try, you fail.

 

[MrSquished]

If you take invermectin, I'm telling you, while jumping up and down really hard, it will bind to the spike protein and fucking destroy covid. It will hurt your body, so you then take hydrochloroquine to help compensate for those side effects. Then for those side effects, you go down to Mar A Lago where Trump will inject bleach and ultra violet light into your anus, and it will fix you right up folks!

 

[Bitek]

An exercise in futility...

Trying to change a trumpanzee's mind by using verifiable facts. No matter how many times you try, you fail.

Ha. There are answers to some of my leading questions at NIH, but the information shows evidence for IVM is pretty weak at best.

The posted review article skips over a lot of the negative commentary and poor results in order to build a stronger case for ivm than the data exists.

Most of the studies are small, flawed design, but still show limited benefit.

Sounds like it's not too dangerous at normal levels, but the in vitro studies that show some effect are at 100x concentrations, and safety data isn't there for that, and it doesn't necessarily translate to effectiveness in vivo.

"Ivermectin has been shown to inhibit the replication of SARS-CoV-2 in cell cultures.13 However, pharmacokinetic and pharmacodynamic studies suggest that achieving the plasma concentrations necessary for the antiviral efficacy detected in vitro would require administration of doses up to 100-fold higher than those approved for use in humans"

I'm all for doing clinical trials. We can use something that helps, but we don't need hyped up drugs that do little, meanwhile we have demonstrably effective vaccines not being used while thousands are dying.
It's fucking stupid that's this is even a national conversation.

 

[jp7794]

I have found that if someone says something like this....

In other words, you have no idea what youre talking about. Do your own research using something other than Google, MSN, or Bing. And if a site is pushing the idea that OK hospitals are backed up with IVM overdoses, run away.

THEY are the one that has no idea WTF they are talking about. "Do your own research, unless it is this or that".

What a colossal turd. Congratulations, so far you are the leading Covidiot. Still a lot of ballgame left though.



Sent from my Pixel 3a XL using Tapatalk

 

[ch33zw1z]

I think it's pretty funny that covidiots would rather swallow an unproven deworming medication than take a vaccine specifically designed to combat this virus.

Like, you get what you get....lol. so glad I'm in MA sometimes.

 

[JD50]

I wasnt stating that. I was addressing the fact many say its for livestock only, when in fact its been used in humans quite a bit. Follow along sparky.

And here's the "who me?" I called a couple pages back.

 

[fskimospy]

How about listening to WHO?

Great, take your own advice and listen to the WHO - ivermectin should not be used to treat COVID.

Again, is your idea that there is some massive conspiracy amongst doctors to not use safe and effective treatments?

 

[Paratus]

I have my vaccine, but thanks for your faux concern.

If thats what you think the current treatment is, youve obviously not read the scientific studies, and blind trials. In other words, you have no idea what youre talking about. Do your own research using something other than Google, MSN, or Bing. And if a site is pushing the idea that OK hospitals are backed up with IVM overdoses, run away.

You didn’t research this throughly or really at all

https://twitter.com/x/status/1427279978673197059

Flawed ivermectin preprint highlights challenges of COVID drug studies

The study’s withdrawal from a preprint platform deals a blow to the anti-parasite drug’s chances as a COVID treatment, researchers say.

www.nature.com

Large Ivermectin Study Retracted

Preprint publisher finds evidence of plagiarism, problems with raw data

www.medpagetoday.com

Though the Elgazzar study is no longer available online, other publications have cited its main findings: Hospitalized patients with COVID-19 who were treated with ivermectin were 90% less likely to die than those who didn't receive the drug.

That conclusion started to fall apart when Lawrence took on a medical school assignment that had him look deeper into the paper. First, he found evidence of plagiarism, with entire paragraphs lifted from press releases and websites, according to The Guardian.

Lawrence also found that the raw data, which are available online for purchase, contradicted the study on several occasions. Gideon Meyerowitz-Katz, an epidemiologist from the University of Wollongong in Australia, also highlighted some of those discrepancies in a Mediumpost.

"For example, the study reports getting ethical approval and beginning on the 8th of June, 2020, but in the data file uploaded by the authors onto the website of the preprint fully 1/3 of the people who died from COVID-19 were already dead when the researchers started to recruit their patients," Meyerowitz-Katz wrote.

"Moreover, about 25% of the entire group of patients who were recruited for this supposedly prospective randomized trial appear to have been hospitalized before the study even started, which is either a mind-boggling breach of ethics or a very bad sign of potential fraud," he continued.


You fell easily for a bunch of bullshit because it came from sources you unskeptically accept.

 

[Paratus]

Ivermectin is a horse medication? Might want to inform WHO. They consider it one of the most important human drugs for humans. Quit spreading lies.

It works against parasites. It doesn’t work against COVID, or treat baldness or make your dick hard.

The WHO has an entire list of important human drugs and since you seemed confused just because they are in that list doesn’t mean they treat COVID.

 

[HomerJS]

What kind of quack would recommend horse dewormer medication to humans?

Overseas Refugee Health Guidance | Immigrant and Refugee Health | CDC

Guidelines for the overseas medical examination for newly arriving US-bound refugees.

www.cdc.gov

Maybe go read your own post and see Ivermectin is begin given for worm infections. Maybe the same reason you don't take nitro glycerin pills for a headache.

 

[HomerJS]

Criminal stupidity by conservatives in Texas. I recall laws were passed having sex with someone knowing you are HIV positive and not informing your partner is a crime. This should be treated in the same way.

Parents find out from other parents that all of school’s kindergarten teachers have COVID-19 (yahoo.com)

 

[DAPUNISHER]

Wife turns vaccine advocate, all it took was her husband dying from it. How many times are we going to read the same story with different players?

https://www.nbcsandiego.com/news/lo...ate-after-husband-dies-from-covid-19/2710063/

This cartoon nails it -

 

[MtnMan]

Wife turns vaccine advocate, all it took was her husband dying from it. How many times are we going to read the same story with different players?

https://www.nbcsandiego.com/news/lo...ate-after-husband-dies-from-covid-19/2710063/

I don't know why this is such a strong sentiment among first responders, but it is. Of course these guys and gals are the ones that run towards what everyone else runs from. I was a volunteer firefighter for 30+ years, so I have some insight to their mindset. To enter a burning structure with temperatures over 400 on the floor, and 1500 at the ceiling with zero visibility tests one metal.

Due to my years as a volunteer firefighter, plus my daughter, and now both of my grandsons are full-time firefighter/EMTs. They have seen many COVID patients in bad shape as part of their job. Yet there is a mindset in the firehouse which have some of the lowest vaccination rates of any group.

I offered $1,000 cash to each as an incentive, and both turned it down.

The oldest grandson (20) is also on the county wide USAR team, and is a swift water rescue technician. This is a team of about 30 people from departments across the county. They were very active during the flooding from Fred a couple of weeks ago.

Yesterday, departments from multiple counties attended the funeral of a member of that USAR team that died of COVID. He was a 28-year-old firefighter/EMT, with a baby on the way.

This past weekend the oldest stopped by the house to borrow something, and it was obvious he was upset about the death of a fellow team member, and told us he had just received the first dose of the COVID vaccine. And told us to tell no one. Only we and his mother know.