It's hard to tell much from a picture, but it looks like there would not be enough depth for that new monitor, and without seeing it you won't know is the thing is even sturdy enough to hold the weight.
The other thing is, PC's today put out lots of heat, and being in an enclosed space like this one has below doesn't help much, even with the door to that area open.
This is not something one can take from the box, assemble, and then return if you decide it won't work for you (most furniture of this type is shipped flat in boxes, and had to be assembled). I'd limit desk purchases to ones you can see first, with a tape measure and the measurements of your components with you. But that's just me.