BadThad, when I look at the TaskManager Networking page, DIMES is making virtually no impact on my available bandwidth. Have you actually tried DIMES and found it caused lagging or just expecting the worst? If you have DSL or Cable internet, I don't think you'll notice. If you have T1 or fractional, then it will not be noticeable.
A more real concern when gaming is the amount of memory the Javascripts can tie up. Though, I've been running Adobe Premiere Pro 1.5.1 with DIMES and DPAD without problem or noticeable lag. PPro is a very memory intensive program.