Unbeknownst to me, I had a PIII-600 CPU fan fail about 2 weeks ago. I used the computer for a good week (8 hours a day) before I realized that my computer was damn quiet, too quiet. Busted open the case to discover that the motherboard fan header must've burned out. Used a 3-pin to molex cable adapter to power the CPU fan, and the machine is running much cooler now. So, yes, even on modern Intel CPUs, you can run without a fan. With an AMD CPU, though, running without a fan is simply suicide.