Honor mode isn't meant for beginners. I'd take it down a level or two to tactician or classic until your familiar with the systems.
Best Tips that worked for me.
-Go a bit martial heavy (ie attack armor) early. Spellcasters tend to bloom later in the game. Early on you don't have enough spells to be rotating through and have to resort to autoattack. However try to get abilities that can allow each character to target both armor types as you go through the game. Make sure everyone has movement skills as well. I went 3 martial (2H Warrior, Rogue, Ranger) v 1 magic (Mag. Damage/Support/Summoner) and it worked well.
-Get the teleport gloves early, its a quest near where you arrive in Fort Joy.
-DOS2 has some walls in exploration. Sometime if you go one direction over another you end up facing enemies above your level that can wipe the floor with you. Its a bit of experimentation to see the "order" in which the game means you to go. This isn't a hard wall if you are a skilled player but for beginners something to keep in mind.
-Before you start conversations in areas that look like battlegrounds spread your party around and put then in tactical locations. DOS2 likes to "ambush" you right after some conversation and you could be in trouble if the enemy AoE's your party down early.
-Update your gear frequently. DOS2 gearing system is well probably the worst thing about it and gear can become obsolete quick. If a fight is too hard try and get some upgrades even if you need to spend cash/steal.