I would have no problem acclimating to iOS since I've used it plenty even though I've never owned an iPhone, my problem is I just don't like it all that much.
To me it feels a bit like the OS X and iTunes from 5 years ago squished into a mobile interface but with 50% of it candy coated thanks to the latest version of the OS. It's not even the smallish screens that bother me - I have a Lumia 521 and ZTE Open (Firefox OS) that are just fine for me to operate, and I used to have a Kin One - it's the interface itself and smallish touch targets of everything within the OS. I know accessibility options and fonts can scale on iOS, it just seems to me that it really wasn't designed to be a mobile OS from the ground up, more like it was shoehorned into that role.
Which is ironic because the OS developer that takes the most flak for putting it's desktop OS into mobile devices - Microsoft - has actually made an OS, Windows Phone, that feels refreshingly simple and easy to use even on ~ 4 inch phones. I find iOS frustrating to use sometimes, and I don't have particularly "fat" fingers. From the home screen to the full screen apps, Windows Phone just feels more consistent in UI design and ease of use, and frankly I think other elements of the OS like the keyboard are better, too.
I like some of the iOS 7 changes (more so on the 5s and to some extent the 5c than on older hardware, where it's still buggy in my experience and from what I've heard), but some of the consistency is gone as a result. They learned from Microsoft's flat design with less skeumorphism, but they injected a far too bright color scheme and transparencies reminiscent of Vista which add nothing to the usability of their devices. The new physics and animations have also done nothing to improve iOS, they are just a new way to make it different and prettier simply because they can - which is kind of the opposite of what modern, clean, flat design is bringing to the table.
I think it's acceptable this round, but I think next generation Apple is going to have the same problem Microsoft did (but to a much lesser extent) with Windows Mobile a few years ago: updating a mobile OS works for about 7 years before users are ready for an entirely new operating system that isn't bogged down by legacy. iOS 7 solves much of the "staleness" of iOS, but I think Apple should be working on something truly new, and not just fingerprint readers and integration with their own future products.
The beauty of Android I think is the flexibility of it, and I'm very much happy with Sense 5.5 on my HTC One. But if I wasn't I could easily flash GPe onto it (had GPe running alongside Sense using a dual boot ROM), or Nova Launcher, or Smart Launcher (which I really like), or any number of other launchers, home screen replacement apps, etc. I even have Giganticon installed, which allows me to scale the home screen icons from normal size all the way up to full screen. Which sounds useless, but having 6 icons on a page Windows Phone style makes it a much more useable interface mounted in my car.
iOS on the other hand both lacks the kind of out-of-box, designed-for-mobile interface that Windows Phone has and the kind of flexibility that Android has. iOS had three big selling points over Android in the past: the lead in apps, but that's dissolving faster and faster with market share; the fluidity or smoothness of the UI, but that advantage is shrinking from Project Butter, Svelte, and ART; and the ease of use, which I think is also disappearing with improvements to Android via both Google and third-party manufacturer "skins" or even forks. Mostly what's keeping users coming back to iOS is ecosystem lock-in, but that's going to slow down as younger users and new users in other countries begin to use and love the other mobile operating systems.
To me the main reason iOS is still a major player is because it was first. If the three major mobile operating systems were released today and branding wasn't a factor it would hardly be the one I would choose. It still has some things going for it like being relatively fast and smooth on the newest of Apple hardware (which they are good at) and the camera is fairly good, but their ecosystem advantage won't last forever. I just don't like the current state of iOS or the future from what I can see for me to be very much interested in it.
I know it sounds like I dislike Apple, but I'm entirely open to switching if I liked the OS. I just don't, and I'm more than happy with Android on my HTC One and Windows Phone even on a low-end model like the Lumia 521. Something like the Lumia 1520 interests me more than going to a smaller screened device like the 5s, even though the 5s has good hardware and the most apps.