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DCal430

Diamond Member
Feb 12, 2011
6,020
9
81
Owned.

Researchers have identified a number of genes associated with the disorder. Studies of people with ASD have found irregularities in several regions of the brain. Other studies suggest that people with ASD have abnormal levels of serotonin or other neurotransmitters in the brain. These abnormalities suggest that ASD could result from the disruption of normal brain development early in fetal development caused by defects in genes that control brain growth and that regulate how brain cells communicate with each other, possibly due to the influence of environmental factors on gene function. While these findings are intriguing, they are preliminary and require further study. The theory that parental practices are responsible for ASD has long been disproved.

What role does inheritance play?

Twin and family studies strongly suggest that some people have a genetic predisposition to autism. Identical twin studies show that if one twin is affected, there is up to a 90 percent chance the other twin will be affected. There are a number of studies in progress to determine the specific genetic factors associated with the development of ASD. In families with one child with ASD, the risk of having a second child with the disorder is approximately 5 percent, or one in 20. This is greater than the risk for the general population. Researchers are looking for clues about which genes contribute to this increased susceptibility. In some cases, parents and other relatives of a child with ASD show mild impairments in social and communicative skills or engage in repetitive behaviors. Evidence also suggests that some emotional disorders, such as bipolar disorder, occur more frequently than average in the families of people with ASD.

It doesn't say genetics are the cause of autism. It says it. At play a role. Idiot. Some cases of autism are genetic, but others are clearly not. There isn't a single cause of autism.
 

Strk

Lifer
Nov 23, 2003
10,198
4
76
It doesn't say genetics are the cause of autism. It says it. At play a role. Idiot. Some cases of autism are genetic, but others are clearly not. There isn't a single cause of autism.

There is no 'clearly not.' It is either genetic or something autoimmune, which is still genetic, but they just aren't sure what the trigger is, kind of like most autoimmune disorders.
 

Pray To Jesus

Diamond Member
Mar 14, 2011
3,642
0
0
Autism is a diverse condition with multiple factors including genetic and environmental, but these factors exist before birth. People are always born with autism.

Environment affects the penetrance of all genetic diseases. The only question is how much of an affect does environment have for a certain genetic disease.
 

Pray To Jesus

Diamond Member
Mar 14, 2011
3,642
0
0
LoL Dcal is an idiot and got owned hard. HAHAH

http://directorsblog.nih.gov/2014/07/29/autism-architecture-unrolling-the-genetic-blueprint/

We know that a combination of genetic and environmental factors influence a child’s risk of autism spectrum disorder (ASD), which is a diverse group of developmental brain conditions that disrupt language, communication, and social interaction. Still, there remain a great many unknowns, including the crucial issues of what proportion of ASD risk is due to genes and what sorts of genes are involved. Answering such questions may hold the key to expanding our understanding of the disorder—and thereby to devising better ways to help the millions of Americans whose lives are touched by ASD [1].

Last year, I shared how NIH-funded researchers had identified rare, spontaneous genetic mutations that appear to play a role in causing ASD. Now, there’s additional news to report. In the largest study of its kind to date, an international team supported by NIH recently discovered that common, inherited genetic variants, acting in tandem with each other or with rarer variants, can also set the stage for ASD—accounting for nearly half of the risk for what’s called “strictly defined autism,” the full-blown manifestation of the disorder. And, when the effects of both rare and common genetic variants are tallied up, we can now trace about 50 to 60 percent of the risk of strictly defined autism to genetic factors.

In the latest study, the Population-Based Autism Genetics and Environment Study (PAGES) team, led by Joseph Buxbaum of the Seaver Autism Center of New York’s Mount Sinai Health System, tapped into the powerful research resource provided by Sweden’s universal health registry. Utilizing blood samples collected by this registry, they examined 500,000 common genetic variants spread across the genomes of 3,046 Swedish individuals—466 with strictly defined autism and 2,580 without. This analysis found that people with strictly defined autism tend to share more of certain genetic variants than people without the disorder. While each particular variant may increase autism risk by just a tiny amount, the researchers found that when the effects of hundreds or even thousands of such variants are added together, the odds of developing autism increase significantly.

The PAGES team then combined these data with those from another Swedish study that’s following more than 1.6 million families with more than 14,000 cases of autism. Using sophisticated new statistical methods to analyze the vast amount of data, Buxbaum’s team was able to calculate what proportion of risk of strictly defined autism is genetic, and which kinds of genetic differences contribute to this.

Specifically, they were able to deduce that inherited common variants account for the bulk of the genetic risk for strictly defined autism. Rare inherited variants that interact with other genes to cause autism account for only a small proportion of risk; rare inherited variants that act alone (including mutations inherited in a recessive pattern), also a small part; and rare, spontaneous mutations, another small part. While spontaneous mutations may be in the minority, researchers noted that they may have a disproportionately large impact, perhaps serving as the final trigger for autism in a person whose genome is already filled with high-risk common variants.

All told, genetic factors appear to explain 50–60 percent of a person’s risk of developing strictly defined autism [2]. That still leaves about half of the risk unexplained, most likely caused by non-genetic factors that are often referred to as “environmental factors.” Such factors, for example, may include the environment of the womb during embryonic development or the chemistry of cells during conception.

The debate about whether genetics or environment is responsible for autism has been intense over the last few years. Clearly this study shows the answer is “both/and” not “either/or.” No doubt there will be lots of additional studies that look at this distribution. But thanks to the collaborative efforts of the PAGES team, we now have a much clearer picture of the genetic “architecture” of strictly defined autism.

The next challenge will be to trace in much greater detail how all of these various genetic factors act individually, as well as in conjunction with one another, to affect brain development. It will also be important to identify how these findings apply to other disorders within the autism spectrum that fall outside the “strictly defined” category. The goal is to translate such knowledge into new strategies for diagnosing, treating, and perhaps even preventing, this extremely challenging group of disorders.
 
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zinfamous

No Lifer
Jul 12, 2006
110,810
29,564
146
LoL Dcal is an idiot and got owned hard. HAHAH

It is 100% true that anyone that ever makes such statements on the internet, is always 100% wrong.

This type of self-aggrandizing behavior is generated only by the type of mind that is capable of accepting self-fulfilling truth, because they are indoctrinated by a system of circular belief that tells them that single books with self-evident truth are equal to real truth.

These people are morons.
 

Stewox

Senior member
Dec 10, 2013
528
0
0
Learned from the chief of NIH's autism research team:

ASD are genetic based conditions that people are born with. There are 100s of genes that can cause ASD. Those genes work together to form systems of pathways that control the growth and pruning of the CNS.

ASD symptoms becomes more noticeable with age. Parents see something wrong with their babies around the time that the MMR vaccines are given.

Owned.

Doubt you learned this because this isn't true. You probably read genetics may play some role.

You're an idiot so I don't give a crap what you think.


Unfortunately DCal340 is correct, most of that "official research" is medical propaganda, most "genetic" diseases are infact not caused genetically, they just blame it on the genes as a cover story.

Most of them are curable, including the ice bucket challenge's ALS: http://www.pharmacistben.com/

https://www.youtube.com/watch?v=br3Z9Prz3Cg
 

Stewox

Senior member
Dec 10, 2013
528
0
0
Honest question. Do you think we landed on the moon?

They did, but the cameras didn't survive the radiation, so they made up the shots, from there most of the conspiracies originate from.

So, even if the conspiracy theories about the pictures can't be true because what they're looking at is not the surface, it's a shopped image, the conspiracy theorists them selfs have partially been correct, because there was stuff classified what was found there, one of the guys talked about it before he died but ofcourse didn't actually reveal what was found, even tho he was slipping some little stuff through without getting the whole thing away.

So it's not about if they went to the moon, it's about what they FOUND on the moon.
 
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shira

Diamond Member
Jan 12, 2005
9,567
6
81
They did, but the cameras didn't survive the radiation, so they made up the shots, from there most of the conspiracies originate from.

So, even if the conspiracy theories about the pictures can't be true because what they're looking at is not the surface, it's a shopped image, the conspiracy theorists them selfs have partially been correct, because there was stuff classified what was found there, one of the guys talked about it before he died but ofcourse didn't actually reveal what was found, even tho he was slipping some little stuff through without getting the whole thing away.

So it's not about if they went to the moon, it's about what they FOUND on the moon.

What significant scientific finding is NOT the product of a conspiracy/propaganda? And how are you able to make that determination? I mean, how can you be sure that a claimed scientific finding isn't just the product of an extremely clever conspiracy that has completely covered its tracks?
 

CitizenKain

Diamond Member
Jul 6, 2000
4,480
14
76
They did, but the cameras didn't survive the radiation, so they made up the shots, from there most of the conspiracies originate from.

So, even if the conspiracy theories about the pictures can't be true because what they're looking at is not the surface, it's a shopped image, the conspiracy theorists them selfs have partially been correct, because there was stuff classified what was found there, one of the guys talked about it before he died but ofcourse didn't actually reveal what was found, even tho he was slipping some little stuff through without getting the whole thing away.

So it's not about if they went to the moon, it's about what they FOUND on the moon.

So you discovered the plot to one of the Transformers movies.
 

OverVolt

Lifer
Aug 31, 2002
14,278
89
91
It doesn't say genetics are the cause of autism. It says it. At play a role. Idiot. Some cases of autism are genetic, but others are clearly not. There isn't a single cause of autism.

Autoimmune disorders seem to be a combination of genetic susceptibility and being exposed to certain antigens. Thing is though, you throw enough antigens at someone and they've likely got a genetic weak link somewhere.
 
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Paratus

Lifer
Jun 4, 2004
16,846
13,778
146
They did, but the cameras didn't survive the radiation, so they made up the shots, from there most of the conspiracies originate from.

So, even if the conspiracy theories about the pictures can't be true because what they're looking at is not the surface, it's a shopped image, the conspiracy theorists them selfs have partially been correct, because there was stuff classified what was found there, one of the guys talked about it before he died but ofcourse didn't actually reveal what was found, even tho he was slipping some little stuff through without getting the whole thing away.

So it's not about if they went to the moon, it's about what they FOUND on the moon.

Bullshit

 
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