The 100k mark is a thing of the past. 200k is the new 100k, IMO.
My 2008 Fusion has 55k miles and still drives like new. I'm hoping to keep it until 150k-200k+.
My fiancee drives a 2003 Malibu with 170k miles. Other than the normal Malibu problems (first three fan speeds died, and a few other quirks) and the AC having a significant leak, it has been a very reliable car. The only major repair we've had to make is a fuel pump at 150k, and all it cost us was $200ish and an afternoon.
I just bought a 2001 Sport Trac with 130k miles. The previous owner was big on maintenance, and it literally drives like new; all it lacks is that new car smell. I'm hoping to keep it in good shape and make it last to 250k+.
My Mustang has 88k original miles. Between all of the power and stress I'll be putting on it, I'm expecting to be doing work on it regularly.