1hr of biking at 25km/h will consume around 700-750 Calories (assume 739 for simplicity). A litre of gas has 739 grams of fuel, which has a bit over 10 Cal per gram. So, 1 litre will take a biker 250km.
Lets take the fuel consumption of an average car to be 10L/100km (23mpg). Covering 250km will consume around 25 litres.
So, 25x.. that's pretty efficient!
What about running? 10km/h (10min mile) will consume 1000 Cal. It'll take a car 7390 to cover the same distance, making the runner only 7x more efficient.
Of course, all this is theoretical and approximate, but it still gives you a clue.
ref
Lets take the fuel consumption of an average car to be 10L/100km (23mpg). Covering 250km will consume around 25 litres.
So, 25x.. that's pretty efficient!
What about running? 10km/h (10min mile) will consume 1000 Cal. It'll take a car 7390 to cover the same distance, making the runner only 7x more efficient.
Of course, all this is theoretical and approximate, but it still gives you a clue.
ref