How Protected Are You Against the Covid Variant JN.1?

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Muse

Lifer
Jul 11, 2001
37,822
8,296
136
I have had 6 covid vaccinations. I think I am pretty much protected.
IMO, it's a mistake to think you are protected by virtue of vaccinations against covid-19, any strain. It mutates really fast, I heard faster than flu or anything. You'll have some protection from the vaccinations. It's gonna help if you're exposed, but you could still get really sick. Mask if you're at risk of exposure. That will reduce your viral load if exposed. That would help a ton in fighting it off.
 

pete6032

Diamond Member
Dec 3, 2010
7,575
3,119
136
What I heard was that annually yes, I am hoping for 2/year. I'd get both for sure. Who knows where we're going from here? If immunity wears off fast enough, annual may not fly.
Yes, I think its going to mutate so fast that every 6 months would be a much better option than annually. That also depends on what researchers can do with the vaccine as well. How quickly can they develop a vaccine after determining that a new variant presents a risk and needs a new vaccine formulation?
 

dullard

Elite Member
May 21, 2001
25,203
3,617
126
Yes, I think its going to mutate so fast that every 6 months would be a much better option than annually. That also depends on what researchers can do with the vaccine as well. How quickly can they develop a vaccine after determining that a new variant presents a risk and needs a new vaccine formulation?
There is work being done on a universal Covid vaccine. Last I looked, they are trying to target the stem between the large spherical virus body and the protein spikes (current vaccines are targeting these spike proteins). This is because the stem is pretty much conserved between strains. The drawback is finding a particle that can convince your body to make antibodies small enough to fit into that space between the spikes and the virus body is tricky. The benefit of never needing to change the vaccine should be obvious--it will always be up to date with the strain that is predominant.

That said, even if a universal vaccine was available, it still wears off after a few months. So quarterly to twice a year vaccinations would still be necessary to maintain most immunity.
 
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Dr. Detroit

Diamond Member
Sep 25, 2004
8,199
663
126
Hey, if you think NY Times readers are dumb, well, where do you go for smarts? Here? Like you said, you didn't even know there were comments to be had reading the NY Times. How smart are you?

I don't go to the comments section "for smarts". Rando's spouting off gibberish with their anecdotal whataboutism's.

How smart am I? Smart enough to realize to not read and put faith into the comments section of random publications.

I did read what the journalist had to say, did you?
  • For many people, the more immunity you’ve built up — through infection, vaccination or both — the milder your symptoms will probably be, Dr. Gordon said. Some people may become infected with JN.1 and experience such mild symptoms that they don’t even realize they are ill, she said. People with compromised immune systems or underlying medical conditions, though, may still have strong symptoms.
 

Muse

Lifer
Jul 11, 2001
37,822
8,296
136
I don't go to the comments section "for smarts". Rando's spouting off gibberish with their anecdotal whataboutism's.

How smart am I? Smart enough to realize to not read and put faith into the comments section of random publications.

I did read what the journalist had to say, did you?
  • For many people, the more immunity you’ve built up — through infection, vaccination or both — the milder your symptoms will probably be, Dr. Gordon said. Some people may become infected with JN.1 and experience such mild symptoms that they don’t even realize they are ill, she said. People with compromised immune systems or underlying medical conditions, though, may still have strong symptoms.
Smarty pants, wow, there's the last word.
 

Zorba

Lifer
Oct 22, 1999
14,822
10,227
136
Husband and I have had every shot that's been available. Seven in all. So far, as well as we can determine, neither of us has had covid. Knock on wood.
7? I've gotten them all but I'm pretty sure I'm only up to 5. Never gotten the Rona, will keep getting boosted. I've had known direct and long exposure multiple times too.

My wife has had every approved manufacturer of vaccine. 2 Novavax in the trail, J&J to get a "legal" vaccine, a Pfizer booster and moderna booster. She didn't get boosted this year because she caught it right before the boosters came out.
 

dullard

Elite Member
May 21, 2001
25,203
3,617
126
She didn't get boosted this year because she caught it right before the boosters came out.
She'll be qualified for this year's booster if she wants a mid-year boost to immunity. Spring time would be halfway to the next booster.
 

manly

Lifer
Jan 25, 2000
11,318
2,344
136
I'm much in favor of an annual Covid vaccination in the fall, but recognize that the vast majority of Americans DGAF anymore. So honestly I don't see the point of a mid-year booster unless a massive wave of Covid hits. I'm not saying don't get one, but what are you trying to achieve? Most experts remind us that the true end goal are milder outcomes, and nearly everyone by now has T cell immunity on their side. (If you're over age 70 or immunocompromised, then you should get vaccinated every fall.)

In general, our federal government needs a better strategy than boosting Moderna's stock price. It's criminal we're paying north of $100 per dose, and we're buying approx. 4 times as many doses as takers in America. Presumably, we're donating some of that abroad before it expires, but I wouldn't be surprised if a lot is simply discarded too.

I don't think it's mutating as fast as those above are claiming. JN.1 is still a variant of Omicron. There is ongoing research into mucosal vaccines.

Current SARS-CoV-2 vaccines provide moderate efficacy against severe disease8,9 but minimal to no efficacy against the acquisition of infection with Omicron subvariants1,2. A key problem is that intramuscular immunization with mRNA and adenovirus-vector-based SARS-CoV-2 vaccines does not typically induce robust mucosal immunity10,11.

 

Dr. Detroit

Diamond Member
Sep 25, 2004
8,199
663
126
I'm much in favor of an annual Covid vaccination in the fall, but recognize that the vast majority of Americans DGAF anymore. So honestly I don't see the point of a mid-year booster unless a massive wave of Covid hits. I'm not saying don't get one, but what are you trying to achieve?

As ~14% of Americans get/got boosted, the majority, as you noted DGAF.
 

KMFJD

Lifer
Aug 11, 2005
29,656
43,847
136
5 vaccines in and 3 infections so far...

I noticed that only very few people are masking up, i was just in Singapore/Thailand/Vietnam/HongKong/Australia and NZ and saw very few people masked up, less than 5% maybe, same thing on planes
 

manly

Lifer
Jan 25, 2000
11,318
2,344
136
5 vaccines in and 3 infections so far...

I noticed that only very few people are masking up, i was just in Singapore/Thailand/Vietnam/HongKong/Australia and NZ and saw very few people masked up, less than 5% maybe, same thing on planes
If those specific countries aren't masking, then I don't feel so bad about Muricans any more.
 
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KMFJD

Lifer
Aug 11, 2005
29,656
43,847
136
Hong Kong seemed to be the most masked up but it really wasn't by much...
 

allisolm

Elite Member
Administrator
Jan 2, 2001
25,009
4,369
136
7? I've gotten them all but I'm pretty sure I'm only up to 5. Never gotten the Rona, will keep getting boosted. I've had known direct and long exposure multiple times too.

Number of shots depends on manufacturer?

1 Jan 21
2 Feb 21
3 Oct 21
4 May 22
5 Oct 22
6 Jun 23
7 Oct 23
All Moderna
 

pete6032

Diamond Member
Dec 3, 2010
7,575
3,119
136
I'm not saying don't get one, but what are you trying to achieve?
Not getting sick. My job doesn't just give out sick time left and right. I was sick for a week with Covid before and it took out all my sick time in one swoop.
 

dullard

Elite Member
May 21, 2001
25,203
3,617
126
So honestly I don't see the point of a mid-year booster unless a massive wave of Covid hits. I'm not saying don't get one, but what are you trying to achieve?
I'm on medication that reduces my immune system. It isn't reduced to nothing (unless I ingest the medication directly), but the medication is intended to suppresses some of my immune system. I also have relatives that are on more fully immunosuppressant drugs (after an organ transplant) and relatives that have most of the underlying risk factors that make them likely to be hospitalized (or worse).

What am I trying to achieve? (1) Since my immune system is weakened, to give it the best shot that I can. (2) Reduce the amount of virus I spread to those relatives. Vaccines are proven to be helpful with both of those. Are vaccines 100% effective at fully eliminating all problems? Certainly not. But they both reduce the incidents of transmission and reduce the severity of the disease when transmission does occur. And since the vaccine effectiveness starts dwindling around the 3-month mark, annual vaccinations leaves ~9 months of higher risk.

What are you trying to achieve by arguing against my ability to get a mid-year vaccine?

As for the rest of your post, the US Federal government no longer buys vaccines for the general public. That ended more than 4 months ago. It still buys it for federal workers, vets, etc like any other vaccine though (just not for the general public). https://www.cdc.gov/vaccines/covid-19/vaccination-provider-support.html
10/6/2023 Update
The US government is no longer purchasing COVID-19 vaccines; therefore, the CDC COVID-19 Vaccination Program has ended.
 
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manly

Lifer
Jan 25, 2000
11,318
2,344
136
I'm on medication that reduces my immune system. It isn't reduced to nothing (unless I ingest the medication directly), but the medication is intended to suppresses some of my immune system. I also have relatives that are on more fully immunosuppressant drugs (after an organ transplant) and relatives that have most of the underlying risk factors that make them likely to be hospitalized (or worse).

What am I trying to achieve? (1) Since my immune system is weakened, to give it the best shot that I can. (2) Reduce the amount of virus I spread to those relatives. Vaccines are proven to be helpful with both of those. Are vaccines 100% effective at fully eliminating all problems? Certainly not. But they both reduce the incidents of transmission and reduce the severity of the disease when transmission does occur. And since the vaccine effectiveness starts dwindling around the 3-month mark, annual vaccinations leaves ~9 months of higher risk.

What are you trying to achieve by arguing against my ability to get a mid-year vaccine?

As for the rest of your post, the US Federal government no longer buys vaccines for the general public. That ended more than 4 months ago. It still buys it for federal workers, vets, etc like any other vaccine though (just not for the general public). https://www.cdc.gov/vaccines/covid-19/vaccination-provider-support.html
Nice straw man. I never argued against your ability or anyone's to get a mid-year vaccine. I specifically encouraged seniors and immunocompromised to get the Covid jab annually; unfortunately many elderly Americans are not. I also suggested that if a big wave of Covid hits, then there's more value to a mid-year vaccination.

I'm in the pro-vaccine camp but most people who have been vaccinated against Covid have contracted Covid. Some before 3 months have passed, others later on. Many multiple times. This is the basic reason why Covid vaccination uptake has dropped so low; most people are fixated on short term transmission rather than long term benefits. It is well known that preventing bad outcomes is the goal here, not preventing contracting a mild case.

If the feds stopped buying vaccine over 4 months ago, that means they still bought tens of millions of doses prior to the fall 2023 vaccination campaign. And IIRC the price we negotiated with Moderna and Pfizer was about 4 times what the Europeans paid for the same vaccines. In the grand scheme of the federal budget, it's not a lot of money but it's still dumb. (My recollection is that we contracted to buy at least 100M doses @ $120 a pop but don't quote me.) Who's buying it wasn't really point though. Taxpayers already made Stephane Bancel a billionaire and he's an ingrate; we shouldn't have to keep rewarding him.

Let me be clear so that you don't misconstrue my thoughts: I encourage you or anyone to get a mid-year vaccine if you wish to. I agree there is value to rejuvenating one's immune response, esp. in the late fall to winter months when respiratory illnesses spread widely. This goes for not just Covid, but also influenza and even RSV for seniors.
 

dullard

Elite Member
May 21, 2001
25,203
3,617
126
Nice straw man. I never argued against your ability or anyone's to get a mid-year vaccine. I specifically encouraged seniors and immunocompromised to get the Covid jab annually; unfortunately many elderly Americans are not...I encourage you or anyone to get a mid-year vaccine if you wish to.

So honestly I don't see the point of a mid-year booster unless a massive wave of Covid hits. I'm not saying don't get one, but what are you trying to achieve? Most experts remind us that the true end goal are milder outcomes, and nearly everyone by now has T cell immunity on their side. (If you're over age 70 or immunocompromised, then you should get vaccinated every fall.)
Please read and reread the three underlined sections. In your first post, you didn't see the point of mid-year and argued for once a year. I'm glad that now you encourage mid-year vaccines, because that is not what your first post said or implied.
 

repoman0

Diamond Member
Jun 17, 2010
4,536
3,442
136
Please read and reread the three underlined sections. In your first post, you didn't see the point of mid-year and argued for once a year. I'm glad that now you encourage mid-year vaccines, because that is not what your first post said or implied.
I read and reread them and I still have no idea where he said you shouldn’t be able to get a vaccine whenever you want if you so desire. He even explicitly said “I’m not saying don’t get one” re: mid-year booster ..
 

manly

Lifer
Jan 25, 2000
11,318
2,344
136
Please read and reread the three underlined sections. In your first post, you didn't see the point of mid-year and argued for once a year. I'm glad that now you encourage mid-year vaccines, because that is not what your first post said or implied.
My comments are in line with what Dr. Paul Offit has said, but people have misconstrued his comments as overly negative toward Covid vaccines. Correct me if I'm wrong, but a lot of developed nations didn't even have a fall 2023 Covid vax campaign. The US CDC kind of stands out in its advocacy at this point, and I'm actually OK with that. I think it's rather unfortunate the percentage of seniors who got the latest jab is pretty damn low.

I could have been clearer but basically for the vast majority of healthy, younger people, the incremental benefit of additional Covid jabs is getting smaller. That should not be construed as discouraging Covid vaccines. I don't personally know Zorba but he's not a retiree, so that was the context in which I made my statements.

For you to then suggest I had argued against your ability to get a mid-year jab is nonsense. I don't know your medical background or anyone else's, nor am I a doctor, to be making targeted medical advice.
 

dullard

Elite Member
May 21, 2001
25,203
3,617
126
I read and reread them and I still have no idea where he said you shouldn’t be able to get a vaccine whenever you want if you so desire. He even explicitly said “I’m not saying don’t get one” re: mid-year booster ..
He said he didn't see the point of mid-year vaccines. You are correct that it doesn't explicitly say you shouldn't get one. But that sure reads to me as an argument against getting it mid-year. He even said the once per year vaccines should be for the over 70 and immunocompromised group. That certainly isn't an endorsement for getting mid-year vaccines either.

Suppose I say that "I see no point in you going to sleep tonight. Those who are below 7 years old should go to bed at least 3 times a week. The federal government spends too much on beds for the Army, 4x what others spend on sleep." What does that imply to you? That I think you should go to sleep tonight?
 
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dullard

Elite Member
May 21, 2001
25,203
3,617
126
For you to then suggest I had argued against your ability to get a mid-year jab is nonsense. I don't know your medical background or anyone else's, nor am I a doctor, to be making targeted medical advice.
I'm slightly immunocompromised and would like the ability to get a mid-year vaccine*. The statement of "If you're over age 70 or immunocompromised, then you should get vaccinated every fall." sure didn't read to me like you are endorsing me to get a mid-year vaccine. In fact, it reads like you think I should get one just every fall.

I'm sorry but I don't know of Paul Offit (I don't think I've ever heard of him) nor do I follow Zorba. So if there are important references there, I missed them.

* Current guidelines allow moderate to severe immunocompromised people to have the option for one more vaccine, as informed by their doctor's clinical judgement.
 
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manly

Lifer
Jan 25, 2000
11,318
2,344
136
I'm slightly immunocompromised and would like the ability to get a mid-year vaccine. The statement of "If you're over age 70 or immunocompromised, then you should get vaccinated every fall." sure didn't read to me like you are endorsing me to get a mid-year vaccine. In fact, it reads like you think I should get one just every fall.

I'm sorry but I don't know of Paul Offit nor do I follow Zorba. So if there are important references there I missed them.
You're putting extra words into my statements that just aren't there, nor implied. I'm encouraging the most at risk classes to get vaccinated every fall, because a lot of them are not. I am NOT saying those are the only people who should get Covid jabs, or that is the ONLY time they should do it.

I find your posting history informative, so I'm not going to go back and forth with you on this any more. I've tried to clear up any misunderstanding earlier but if you want to persist in accusing me of saying something that I didn't, then frankly that's not cool.
 

WelshBloke

Lifer
Jan 12, 2005
30,937
8,668
136
I'm in the pro-vaccine camp but most people who have been vaccinated against Covid have contracted Covid. Some before 3 months have passed, others later on. Many multiple times.
I'm going to riff off this and it isn’t particularly aimed at you!


Vaccines won’t stop you catching something. They aren’t a magic barrier that prevents a virus from touching you!

What they do is give your body a heads up at what to expect when a particular virus infects you, and then your immune system can get straight to work munching up the virus rather than wasting time working out what the hell is going on!

Obviously for this to happen you have to actually have the virus in your system. If you’re lucky your immune response will handle the infection before you know you have it and even if you still get a bad dose then you can be assured that it would have been worse if your body had let the virus multiply while it worked out what was happening!

I've seen quite a few people die from COVID, I'm fairly fit and well but I absolutely will have all the vaccines after having worked through the first waves of COVID.
 

manly

Lifer
Jan 25, 2000
11,318
2,344
136
I'm going to riff off this and it isn’t particularly aimed at you!


Vaccines won’t stop you catching something. They aren’t a magic barrier that prevents a virus from touching you!

What they do is give your body a heads up at what to expect when a particular virus infects you, and then your immune system can get straight to work munching up the virus rather than wasting time working out what the hell is going on!

Obviously for this to happen you have to actually have the virus in your system. If you’re lucky your immune response will handle the infection before you know you have it and even if you still get a bad dose then you can be assured that it would have been worse if your body had let the virus multiply while it worked out what was happening!

I've seen quite a few people die from COVID, I'm fairly fit and well but I absolutely will have all the vaccines after having worked through the first waves of COVID.
Out of curiosity, what did the NHS do with the new Covid jab this past season? Was it strongly promoted and was it available to all who wanted it, or just some?
 

WelshBloke

Lifer
Jan 12, 2005
30,937
8,668
136
Out of curiosity, what did the NHS do with the new Covid jab this past season? Was it strongly promoted and was it available to all who wanted it, or just some?
I had mine at the hospital (as I have with all my other jabs) and that was offered to all frontline staff (we get annual flu jabs at the same time).

My mum got hers as she’s over the age limit.

My wife was too young to get hers and they weren’t giving this one out to the kids (I think).

So basically if you are eligible the NHS will contact you and arrange a jab.
 
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