My current ASUS was very finniky, now it's just broken. My ASUS board used to work fine on a fresh window's install, but every time I would finish installing the drivers for video card and chipset it would start to BSOD on restart and require me to shut down. I tried flashing to the newest BIOS at that time and it seemed cut the BSOD rate in half. Sometimes it would just lock up. It works if you shut it down then. Then I got a new CPU and flashed to the newest BIOS and now the board just locks up when I send a reset signal. If I shut down it works fine. This is annoying because when I make BIOS changes about 50% of the time it will hang, give a BEEP, and then shut off. When I restart it defaults to the default setting because it says OC failed... which is not the case because it wasn't overclocked. This is the most unstable motherboard I've had.
That said, I had an MSI board die on me once when after about 6 months of ownership I turned it on and it smoked burning a trace near the PCI slot containing my network card. No blown up caps. It could have been the fault of the network card, who knows.
I had an EPOX board die one day when I plugged in a USB flash drive. There was a tiny static charge and the screen froze...then the board wouldn't post.
I've owned 3 Abit boards with no issues, 1 MSI board that ran until I upgraded, and one Gigabyte board that did the same.
So, ASUS is the only one I've had that just didn't work very well. My other motherboar deaths were not really the fault of the motherboard. Also, as others have said the ASUS website is terrible. It seems to work about 75% of the time. From now on I'll likely go Gigabyte.