if you take your system apart often enough, even if only partially, it saves a ton of time and hastle vs having to unscrew everything every single time. that and i have had issues in the past with low quality screws breaking off midway out of things like hard drives and what not, which really sucks because it's a major pain in the ass to re-drill the mounting holes, let alone re-thread them. generally once they have been re-drilled i try to find a tool free drive bay to put it in somewhere in my collection of cases lol