Simply go to the BIOS
- Hit up the multiplier to around 43-44 and work your way from there assuming you want to push the Vcore and clocks a bit
- Internal PLL on, LLC ultra-high, but can be reduced a bit from then on depending on stability
- Spread Spectrum on ASUS boards as they claim it can enhance stability, haven't had issues
- Don't use OC Tuner/Auto-OC as it sets ridiculous Vcore presets for relatively low clocks (1.4 passed easy because of it)
- XMP Profile for the RAM, don't worry about the IMC and degradation if its 1.65+, but you can test stability for a slightly lower voltage like 1.4v
- Once you find stability at a preset Vcore, add a small minus offset to reduce degradation and allow it to dip according to load/speed
- Disable virtualization
Open the system, download Prime95 26.6v and not anything newer because of ridiculous AVX based strain for newer procs, HWmonitor/Coretemp/HWinfo or the first two mainly for temps and vcore, maybe even CPU-z, Intelburntest to shorten stability testing a bit, and any version of local memtest (HCI) for memory stability
Hit the processor with Prime95 (preferably) and Small FFTs (Blend preset is a bit weaker and thus comparatively cooler on load) and hit it for at least 2 hours to assess theoretical stability under load. Temps will fly, but beneath 75C max is alright. Your goal is maximum stability and not a hair more. Don't worry about 100% load in typical usage scenarios, 75 doesn't mean temps will exceed 65C in modern games.