Declare martial law, round up all members of Congress and the Supreme Court and ban them from ever holding office again.
Fire any civil service employee who was not hired through the standard hiring/recruitment system and have them re-apply for their jobs. Ban nepotism within the same Dept. and prosecute any and all elected officals and/or their agents who violate that rule.
Announce edicts that there will be Zero tolerance for corruption of all newly elected, appointed officials and any federal employees. Any person found guilty will be jailed for life, no exceptions.
Ban any and all lobbyists from setting foot in Washington DC. All lobbying will be done in writing and filtered through the Office of Gov't Ethics. Any lobbyist found violating the edict by directly communicating with any elected or appointed official, their agents and any other federal employee will be jailed for life for sedition and for attempting to corrupt a gov't official.
Give authority to the FBI, the Secret Service and the intelligence agencies to freely monitor the activities of all elected and appointed officials, and have all elected, appointed and hired federal gov't employees sign a waiver stating that they willingly give up their constitutional rights to enter gov't service.
All election campaigning for federal office will be financed through the federal gov't. All campaign contributions will be deposited in a special account and evenly distributed amongst all candidates seeking federal office on a scale commensurate with their office.
Give the Office of Gov't Ethics all the power and financing they need to sniff out and smother corrupt office holders.
Introduce term limits for all members of Congress, Justice and the Supreme Court with the idea in mind that the longer one stays in office the more corrupt they become.
Finally, resign myself from office and retire on a nice fat gov't pension.
*End of pipe dream*
edit - And just for the hell of it, require any and all elected, appointed or hired federal employee to serve at least two years in the military branch of service of their choice prior to holding any other federal job. HA!