^ It does save energy and that's why most systems have vents with dampers. You just don't want to overdo it.
Your linked article was wrong in some respects. If it's a high efficiency motor that ramps up in speed, you're still getting a higher % of airflow in the target areas, and that supposed lower efficiency is just lost as heat, in the airflow stream, blown into the target rooms. It states the lower efficiency PSC blower will move less air, but it ignores that more, warmer air will reach the target rooms.
It goes on to mention duct leakage but that's essentially what open vents you don't need hot air through are, wasted leakage out of the system where you don't need heat to go. It also bases it all on a an unrealistic assumption "If it’s a typical duct system with 60% higher static pressure than the maximum specified".
The article is talking about extreme cases. We've had our vents adjusted for several years. No cracked heat exchanger, no blower motor failure. The ironic part is the #1 cause of blower motor failure is our throwaway society where homeowners aren't instructed to relube the blower bearings every few years, to instead consider it a non- serviceable, disposible item. While the blower motor is being serviced, the fan blades should be cleaned and of course the filter should be kept clean.
You can't just blindly close ducts, instead taking it upon yourself to check the operation of the system and better maintain it (the way it was supposed to be in the first place).