I work with adaptive technology for the disabled in a univerity setting.
Our clients all use JAWS from henter-joyce and
www.hj.com.
They also have screen magnification software called Magic.
The kicker is that most software of this nature is REAL picky about what video card you have and what version of the driver you are using.
For a plethora more information on what adaptive technology has to offer, check out
webABLE
Private message me if you want any more info.