most definately give it a try...What have you got to lose? Like I said, as long as the mem bus is set to 100 mhz, all should be good. On my wifes' OC-ed Celeron system, I am running 1 stick of 128mb PC 100 and 1 stick of Micron PC133. If it don't work...Well, then lay out a whopping $18 for another PC133 stick.. Really, the only memory that you can't mix is VC133 and PC133.