grrl-
It all depends on your hardware. I would check for Win2K drivers for all your hardware BEFORE you decide to take the plunge. My first experience with it was terrible, but then again the driver support was almost non-existant. Plus I make sure I do all the updates, including the latest service pack, which can take quite a while to download depending on your connection. I'm very impressed by the stability of this OS. It's not perfect of course, don't get deulsions that all your problems will disapeer. Plus I like the thought that this release is optimized for newer processors like the PIII and the Athlon, whereas 98 and 98SE were optimized for older procs.
If you have any more questions or problems, let me know, I'd be happy to help.