Well, technically, if you have cameras tracking the absolute positions of the head and pinnae, it may be possible.Active noise cancellation across the entire audio spectrum in all locations of an open room is mathmatically impossible.
But yes, without measuring the position, it should be impossible.
OP, put some more thought into an insulated enclosure. A box built with panels that are constrained-layer-damped, with baffled air pathways, can achieve a significant insertion loss across a wide frequency range with little restriction in airflow.
EDIT: Is this a Rittal electrical panel? How big is it?
EDIT2: http://www.lytron.com/Tools-and-Tec...-Special-Applications-and-Fluid-Compatibility This is a chiller that can handle PAO dielectric fluid. Very little risk of shorting out components. You could hook it up to a heat exchanger inside the panel, and blow the fans across it instead of bringing in fresh air all the time.
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