I think I heard on a radio newscast that it could be stored with dry ice.. Anyway I wonder how long the vaccine is stable at temps above freezing.. Obviously they cant inject with something too cold and cause something like frostbite or worse
It's based on RNA, which is very unstable. For long term storage, it needs to be kept at -70-80. RNA is OK at 4 degrees or so for most of a day, but if you leave it out at room temperature, it can start to degrade within an hour.
The likely protocol would be to thaw out your stock for the days use (r maybe every 4 hours or so), and keep working, ready injections at 4c.
Dry Ice is ~- 70 C, and generally used when shipping sensitive materials, or as emergency backup injection for -80 freezers, and also as a source for large, -20 C closets. It's definitely reasonable to keep vaccine in Dry Ice coolers, say if you are operating a remote clinic, out in in a parking lot or something, so long as you have enough of it so that it won't sublimate by the end of the day. (for shipping purposes, assuming you know how to pack it, it's usually 5lbs / 24 hours in a proper styrofoam cooler--but that assumes you aren't accessing it constantly).
A remote vaccination center could be very effective with a couple of large dry ice coolers (25lbs each, I'd say), some microfridges, and of course whatever sterile workspace/hood is required. I have no idea if these have to be prepared after thawing, or if it's just thaw and inject?
heh, injecting "too cold" isn't a problem. It's probably what, 1cc per dose? Not only is that not going to affect your body temperature or give you frostbite, that volume is easily hand-warmed within a minute or so.