NON_POLITICAL China Coronavirus THREAD

Page 479 - Seeking answers? Join the AnandTech community: where nearly half-a-million members share solutions and discuss the latest tech.

allisolm

Elite Member
Administrator
Jan 2, 2001
25,009
4,369
136
"Texas becomes the first US state with more than 1 million Covid-19 infections."

My daughter, SIL, grandson and nephew live in TX.

I'm in FL and we're trying to catch up to TX - 1/4 the size of TX, 3/4 the population and 85% as many cases.
 
Last edited:

zinfamous

No Lifer
Jul 12, 2006
110,803
29,553
146
Reactions: skyking

K1052

Elite Member
Aug 21, 2003
46,752
34,631
136
I think I heard on a radio newscast that it could be stored with dry ice.. Anyway I wonder how long the vaccine is stable at temps above freezing.. Obviously they cant inject with something too cold and cause something like frostbite or worse

So Pfizer is shipping vaccine in containers using dry ice that can be refilled to maintain -70C but there are concerns about keeping doses longer than a week or two in them, the potential for dry ice shortages (apparently bulk CO2 mostly comes from ethanol production which has been low), and how frequently they can be opened. Also they're packaged in lots of 1000 which in rural settings is possibly more than you want to defrost at a time. Once warmed it sounds like the vaccine is fridge stable for a few days before it probably has to be tossed as spoiled.

Given limited quantities and the limitations facilities that can document ultra cold freezer storage capability are almost certainly going to get preference in shipments. This will mostly include urban areas with big wealthy hospitals and biotech research institutions both public and private. College towns also probably favored is their universities might have the equipment on hand for loan to local health authorities and/or the $ to buy.
 

zinfamous

No Lifer
Jul 12, 2006
110,803
29,553
146
Last test was negative.

I thought there were very few people wearing masks at the West Georgia Flea Market on Saturday, but then I drove a couple hours away to "Mountain Top Flea Market" in Alabama and couldn't believe it was so much worse. You could look at a sea of people and have trouble spotting a single one with a mask. Occasionally you'd see someone wearing a neck gaiter or something but they'd have it pulled down around their neck even when interacting with others. I had probably walked a mile and a half there before finally seeing a woman with a mask but her two children were mask-less... and then her husband or boyfriend or whoever showed up and embraced her without a mask. Their household obviously isn't doing much to slow it even if one person had a mask.

Strangely, when vendors see you wearing a mask at the Georgia flea market you will get harrassed to buy masks. They see you as one of the few potential customers. Only one vendor there seems to be vocally anti-mask and she does not fit the stereotype (minority; not a white Georgian redneck).

Out of curiosity, why do you take the test so frequently? I maybe missed something about your line of work or something.

I have free testing at work (Still haven't signed up for it; keep forgetting), but I also take public transit now 1.5 hours each way, every day. ...Still haven't been bothered to take the test. Don't know why, it's indeed somewhat stupid. Train has been mostly OK, but as each week goes on, I'm noticing it get slightly more and more crowded, and with sketchier assholes just paying any fucking attention to distancing. Also, if I'm doing a half shift, that mid-day crowd is waaaaaay different than the rush hour, 9 to 5 crowd, lol. A lot more people, too. I've noticed this in the past. It's like we are two completely different societies from the labor perspective.
 
Reactions: CZroe

CZroe

Lifer
Jun 24, 2001
24,195
856
126
Out of curiosity, why do you take the test so frequently? I maybe missed something about your line of work or something.
My previous post about it (before results) described that I had some FLI symptoms and needed to know if I had just passed it on to a food service employee.

Well, I just got tested again this morning. Had mild congestion with a little blood in my mucous, some occasional sneezing, and a tickle in my throat. Testing was the least I could do after what happened last night:
I went through the McDonald's drive-thru. They handed me my food and no one was in front of me when I started moving forward, window down since I was still holding the food and managing a manual transmission. Before setting it down I felt to make sure both items were in there. Hands full, I glanced down to scout a place for the bag. At that moment I suddenly had to sneeze and did not have a free arm to sneeze into.

Since I'd already pulled forward enough to clear the pick-up window and there was just a brick wall next to me, I thought the coast was clear to sneeze out of the open window. I turned my head and sneezed just as I was reaching the corner of the brick wall, which should not have mattered since the lobby was closed and there shouldn't be customer traffic there (drive-thru only). Turns out, some McDonald's employee stepped out the corner door and into the line of fire right as I was projectile-sneezing directly at them from only a yards away... completely unstifled. I sneezed hard enough I probably sent rockets of spit hurling the full distance. Oops.
Sneezing was the first sign but I had more symptoms in the morning so it was the least I could do.


...oh yeah: and it's free, so any excuse to justify it to myself works. I've had it about once a month since mid-summer.
 
Last edited:
Reactions: zinfamous

IronWing

No Lifer
Jul 20, 2001
69,474
27,749
136
I'm calling BS on the claim that rural hospitals can't afford a $10-15k freezer. They ain't that poor and chances are that they already have one. College microbiology labs have deep freezers and their budgets are far lower than rural hospital budgets.
 

zinfamous

No Lifer
Jul 12, 2006
110,803
29,553
146
I think I heard on a radio newscast that it could be stored with dry ice.. Anyway I wonder how long the vaccine is stable at temps above freezing.. Obviously they cant inject with something too cold and cause something like frostbite or worse

It's based on RNA, which is very unstable. For long term storage, it needs to be kept at -70-80. RNA is OK at 4 degrees or so for most of a day, but if you leave it out at room temperature, it can start to degrade within an hour.

The likely protocol would be to thaw out your stock for the days use (r maybe every 4 hours or so), and keep working, ready injections at 4c.

Dry Ice is ~- 70 C, and generally used when shipping sensitive materials, or as emergency backup injection for -80 freezers, and also as a source for large, -20 C closets. It's definitely reasonable to keep vaccine in Dry Ice coolers, say if you are operating a remote clinic, out in in a parking lot or something, so long as you have enough of it so that it won't sublimate by the end of the day. (for shipping purposes, assuming you know how to pack it, it's usually 5lbs / 24 hours in a proper styrofoam cooler--but that assumes you aren't accessing it constantly).

A remote vaccination center could be very effective with a couple of large dry ice coolers (25lbs each, I'd say), some microfridges, and of course whatever sterile workspace/hood is required. I have no idea if these have to be prepared after thawing, or if it's just thaw and inject?

heh, injecting "too cold" isn't a problem. It's probably what, 1cc per dose? Not only is that not going to affect your body temperature or give you frostbite, that volume is easily hand-warmed within a minute or so.
 
Reactions: Denly and skyking

K1052

Elite Member
Aug 21, 2003
46,752
34,631
136
A remote vaccination center could be very effective with a couple of large dry ice coolers (25lbs each, I'd say), some microfridges, and of course whatever sterile workspace/hood is required. I have no idea if these have to be prepared after thawing, or if it's just thaw and inject?

I think some countries basically plan to do this. The Brits have a very detailed plan about containerized clinics they can haul around and the Germans are setting up centralized government inoculation facilities. We're just going to throw vaccines at the states and say "figure it out".
 

zinfamous

No Lifer
Jul 12, 2006
110,803
29,553
146
I'm calling BS on the claim that rural hospitals can't afford a $10-15k freezer. They ain't that poor and chances are that they already have one. College microbiology labs have deep freezers and their budgets are far lower than rural hospital budgets.

yeah, they aren't very expensive and it's weird to think that a clinic can't access one--I understand that many of them won't have them (not all clinics are set up for tissue collection), or certainly that a CVS or Walgreens wouldn't have one, but they can definitely afford them.

Speaking of....I know of one that is soon to be replaced at my previous lab, relatively new (5 years old), because the compressor is junk and keeps crapping out. Not to worry for keeping vaccines, though....just don't leave the door open for more than 15 seconds at a time and it seems to be OK.
 

CZroe

Lifer
Jun 24, 2001
24,195
856
126
Train has been mostly OK, but as each week goes on, I'm noticing it get slightly more and more crowded, and with sketchier assholes just paying any fucking attention to distancing. Also, if I'm doing a half shift, that mid-day crowd is waaaaaay different than the rush hour, 9 to 5 crowd, lol. A lot more people, too. I've noticed this in the past. It's like we are two completely different societies from the labor perspective.

Everywhere I go I hear constant coughing even as you hear PA announcements telling people to stay out or return home if they have symptoms. It's usually worse since I also see them doing stupid things like pulling their mask down to cough into their hand. Even today, I saw a Hardee's employee use her mouth to open a coffee packet while also contaminating her hands (I'm sure she would've washed or gloved before dealing with customers, but still...). It's a freakin' circus out there. Even going to vote I was surrounded by people coughing, hacking, and wheezing who absolutely should not be out. I'm finding myself in the same room as these people far too often.
 

amdhunter

Lifer
May 19, 2003
23,324
219
106
I'm calling BS on the claim that rural hospitals can't afford a $10-15k freezer. They ain't that poor and chances are that they already have one. College microbiology labs have deep freezers and their budgets are far lower than rural hospital budgets.
That $15k freezer probably costs $75k after medical markup...
 
Reactions: Captante

skyking

Lifer
Nov 21, 2001
22,215
5,075
146
My sister's family has had a pretty rough go this year. One of my nieces died from colon cancer, her sister did survive but had it too. The day after they buried her, their mother lost her foot to infection. Their father has been in the hospital for a while, now he's in a nursing home rehabbing.
That was early summer. Fast forward to today, niece developed symptoms a few days ago and her and BF are positive. She is feeling better.
This morning my sister is in the hospital with shortness of breath.
She is strong, but is a 76 year old diabetic amputee.
 
Last edited:

Ajay

Lifer
Jan 8, 2001
16,094
8,106
136
I'm calling BS on the claim that rural hospitals can't afford a $10-15k freezer. They ain't that poor and chances are that they already have one. College microbiology labs have deep freezers and their budgets are far lower than rural hospital budgets.
Many have gone bankrupt in recent years. As more people drift towards urban centers, there often isn't enough revenue coming in to support a hospital. So, without government support, their financial situation would be even worse if they had to buy ultra low temp freezers.

From @K1052 's recent post:
CDC Director Robert Redfield has said Congress will need to provide up to $6 billion for vaccine distribution, but funding negotiations stalled ahead of the election. To date, the federal government has allocated 3% of that amount, $200 million, to the states to immunize the nation.
 

skyking

Lifer
Nov 21, 2001
22,215
5,075
146
my wife is the capital purchaser for a large hospital system. About 6 weeks ago the feds started buying up those deep freezers and they lost the ability to purchase any.
 

ch33zw1z

Lifer
Nov 4, 2004
37,968
18,284
146
my wife is the capital purchaser for a large hospital system. About 6 weeks ago the feds started buying up those deep freezers and they lost the ability to purchase any.

Interesting. Wonder what the mark up will be when the states need them. Or if states in political favor will have first dibs at a discount
 
sale-70-410-exam    | Exam-200-125-pdf    | we-sale-70-410-exam    | hot-sale-70-410-exam    | Latest-exam-700-603-Dumps    | Dumps-98-363-exams-date    | Certs-200-125-date    | Dumps-300-075-exams-date    | hot-sale-book-C8010-726-book    | Hot-Sale-200-310-Exam    | Exam-Description-200-310-dumps?    | hot-sale-book-200-125-book    | Latest-Updated-300-209-Exam    | Dumps-210-260-exams-date    | Download-200-125-Exam-PDF    | Exam-Description-300-101-dumps    | Certs-300-101-date    | Hot-Sale-300-075-Exam    | Latest-exam-200-125-Dumps    | Exam-Description-200-125-dumps    | Latest-Updated-300-075-Exam    | hot-sale-book-210-260-book    | Dumps-200-901-exams-date    | Certs-200-901-date    | Latest-exam-1Z0-062-Dumps    | Hot-Sale-1Z0-062-Exam    | Certs-CSSLP-date    | 100%-Pass-70-383-Exams    | Latest-JN0-360-real-exam-questions    | 100%-Pass-4A0-100-Real-Exam-Questions    | Dumps-300-135-exams-date    | Passed-200-105-Tech-Exams    | Latest-Updated-200-310-Exam    | Download-300-070-Exam-PDF    | Hot-Sale-JN0-360-Exam    | 100%-Pass-JN0-360-Exams    | 100%-Pass-JN0-360-Real-Exam-Questions    | Dumps-JN0-360-exams-date    | Exam-Description-1Z0-876-dumps    | Latest-exam-1Z0-876-Dumps    | Dumps-HPE0-Y53-exams-date    | 2017-Latest-HPE0-Y53-Exam    | 100%-Pass-HPE0-Y53-Real-Exam-Questions    | Pass-4A0-100-Exam    | Latest-4A0-100-Questions    | Dumps-98-365-exams-date    | 2017-Latest-98-365-Exam    | 100%-Pass-VCS-254-Exams    | 2017-Latest-VCS-273-Exam    | Dumps-200-355-exams-date    | 2017-Latest-300-320-Exam    | Pass-300-101-Exam    | 100%-Pass-300-115-Exams    |
http://www.portvapes.co.uk/    | http://www.portvapes.co.uk/    |