Ive had the PA246Q for a couple months now and really like it. You can see my write up of it on the LCD Sticky. Dont worry about wide gamut as ASUS did a good job of both factory color calibration as well as provided the needed alternate modes (eg, sRGB, AdobeRGB, Standard, User, Scenery, Theater) to allow you to get whatever you want/need.
No one seems to mention the significant important implementations ASUS has done with this monitor (which really is a modified DELL U2410 - same LG panel and basic electronics). For example, the SIX axis color correction has all the degrees of freedom to adjust color in a way you should ever need or want and the ASCR option in Theater mode renders great blacks with movies. The powerful CCFL effortlessly is able to provide rich/luxurious colors. If you dont want the wide gamut then just choose sRGB, Standard mode or just calibrate your own preference in User mode. No one ever mentions that this monitor is custom calibrated at the factory, comes with a calibration report for YOUR SERIAL NUMBER AND INCLUDES THE UNIQUE "INI" FILE FOR YOUR SERIAL NUMBER DERIVED AT THE FACTORY DURING THE CUSTOM CALIBRATION (file is on included CD for use with your photo shop application).
Over all Im satisfied.
In terms of display quality/imperfection, probably the weakest area of this monitor might be IPS glow. In a dark room, the glow can be quite noticeable. (The old no longer available expensive IPS "WXI" NECs used a TW polarizer to suppress this effect.) In normally lighted room/office the ASUS's glow is effectively unnoticeable or irrelevant.
If you decide to purchase this monitor, be sure to use the DVI option as I found that text was perceptibly crisper than with VGA. (Use of VGA seemed to result in text having a slight shadow or reflection like artifact, but cleaned up with instead using DVI.)
The problem, again, with factory calibration, or ANY calibration for that matter, is that it does, and WILL drift over time. For color-critical applications it's recommended you re-calibrate weekly, or before starting work on a big project. Otherwise, on my NEC at least, I've measured the drift becoming apparent (dE > 2) in about 3 months time.
Another thing is that "sRGB" modes on most of these wide gamut monitors typically only try to emulate it, and are unable to be calibrated very well, if at all. Of course, my research is a few years out of date at this point, so I don't know if that specific monitor has improved on it. To my understanding, the best case is to actually have the LCD itself do hardware gamut-conversion, and allow for calibration of the new gamut.
The A-TW polarizer is nice, but the side effect is that you do get a slight magenta and green hue when viewed at extreme angles against darker colors.
Finally, never use VGA with LCD's if you can help it. VGA provides an analog signal, which was great for a CRT, but not so much for an LCD, where its pixels are of a fixed size. Feed it with only digital signals (DVI, HDMI, etc.) when at all possible.