Pffft! Who needs Pfizer vaccine? Moderna's has ~95% effectiveness and doesn't need dry ice to stay fresh

Muse

Lifer
Jul 11, 2001
37,833
8,302
136
Estimated 1 billion doses possibly available in 2021. Heard about it today on NPR. Their trial had 90 cases in the placebo group and 5 that got the vaccine, translates to almost 95% effective. Said to be especially effective for the elderly.


Stays fresh without intense refrigeration unlike the Pfizer vaccine.

In Moderna's trial, 15,000 study participants were given a placebo, which is a shot of saline that has no effect. Over several months, 90 of them developed Covid-19, with 11 developing severe forms of the disease.

Another 15,000 participants were given the vaccine, and only five of them developed Covid-19. None of the five became severely ill.
 
Last edited:

pete6032

Diamond Member
Dec 3, 2010
7,578
3,123
136
Estimated 1 billion doses possibly available in 2021. Heard about it today on NPR. Their trial had 90 cases in the placebo group and 5 that got the vaccine, translates to almost 95% effective. Said to be especially effective for the elderly.


Stays fresh without intense refrigeration unlike the Pfizer vaccine.
Frankly I think articles like this are wholly inappropriate at this time. We don't know anything about how well these vaccines performed for specific groups of people, and to say that one vaccine is better than the other without examining any of the underlying data is irresponsible and poor journalism.
 

Muse

Lifer
Jul 11, 2001
37,833
8,302
136
From NYTimes article about Moderna's and Pfizer's vaccines:

The companies’ products open the door to an entirely new way of creating vaccines — and creating them fast. Both use a synthetic version of coronavirus genetic material, called messenger RNA or mRNA, to program a person’s cells to churn out many copies of a fragment of the virus. That fragment sets off alarms in the immune system and stimulates it to attack, should the real virus try to invade. Although a number of vaccines using this technology are in development for other infections and cancers, none have yet been approved or marketed.

“The fact that two different vaccines made by two different companies with two different kinds of structures, in a new messenger RNA concept, both worked so effectively confirms the concept once and for all that this is a viable strategy not only for Covid but for future infectious disease threats,” said Dr. Barry R. Bloom, a professor of public health at Harvard.
 
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Muse

Lifer
Jul 11, 2001
37,833
8,302
136
Frankly I think articles like this are wholly inappropriate at this time. We don't know anything about how well these vaccines performed for specific groups of people, and to say that one vaccine is better than the other without examining any of the underlying data is irresponsible and poor journalism.
Nonsense. They are early studies, not peer reviewed, but to say they are promising is a gigantic understatement.

Additional info from the NYTimes article:

The 95 cases included 15 people 65 or older and 20 people who were Hispanic, Black, Asian or multiracial. The company said the vaccine appeared equally safe and effective in all the subgroups.

The results were analyzed by an independent data safety monitoring board, appointed by the National Institutes of Health.
 

sandorski

No Lifer
Oct 10, 1999
70,127
5,657
126
Looks promising. Hopefully in the next 6 months or so we can resume Pre-Covid-19 existence. Psychologically it will take more time, but at least the weight of all this will be lifted off our shoulders.
 

kage69

Lifer
Jul 17, 2003
28,019
38,496
136
Yeah the storage temp difference is epic, that will make things a lot easier for rural communities. Moderna is saying they can crank out 20million doses by years end. Outstanding, keep it up guys. I hope they outsource production much as possible to other companies. Maybe that number can be boosted.

94.5% effectiveness, and no safety and review protocols skipped. No wonder Polonium Putin has Fancy Bear trying to steal/sabotage covid research data, makes Russia medical science look shoddy and amateur by comparison.

Wife had a stroke last year, is high risk for this clot producing virus. Hopefully she can get that At Risk early access. For 94.5% effectiveness I'd pick it up in person if necessary.
 

Thump553

Lifer
Jun 2, 2000
12,726
2,501
126
Is Moderna's vaccine a single dose? As I recall Pfizer requires two doses 21 days apart.
 

Thump553

Lifer
Jun 2, 2000
12,726
2,501
126
Looks promising. Hopefully in the next 6 months or so we can resume Pre-Covid-19 existence. Psychologically it will take more time, but at least the weight of all this will be lifted off our shoulders.

I doubt greatly us ordinary folks will see any vaccine within six months. I'm thinking near end of 2021 or thereabouts, hopefully I get proven wrong.
 
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mxnerd

Diamond Member
Jul 6, 2007
6,799
1,101
126
Estimated 1 billion doses possibly available in 2021. Heard about it today on NPR. Their trial had 90 cases in the placebo group and 5 that got the vaccine, translates to almost 95% effective. Said to be especially effective for the elderly.


Stays fresh without intense refrigeration unlike the Pfizer vaccine.

Wow, that's impressive! The best part is that it does not require low temperature like Pfizer's.
 
Reactions: Muse

Muse

Lifer
Jul 11, 2001
37,833
8,302
136
Yeah the storage temp difference is epic, that will make things a lot easier for rural communities. Moderna is saying they can crank out 20million doses by years end. Outstanding, keep it up guys. I hope they outsource production much as possible to other companies. Maybe that number can be boosted.

94.5% effectiveness, and no safety and review protocols skipped. No wonder Polonium Putin has Fancy Bear trying to steal/sabotage covid research data, makes Russia medical science look shoddy and amateur by comparison.

Wife had a stroke last year, is high risk for this clot producing virus. Hopefully she can get that At Risk early access. For 94.5% effectiveness I'd pick it up in person if necessary.
Personally, I'd take it today if they'd give it to me.
 
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cytg111

Lifer
Mar 17, 2008
23,537
13,109
136
I doubt greatly us ordinary folks will see any vaccine within six months. I'm thinking near end of 2021 or thereabouts, hopefully I get proven wrong.
If contact numbers be dropping it doesnt really matter
 

Muse

Lifer
Jul 11, 2001
37,833
8,302
136
I doubt greatly us ordinary folks will see any vaccine within six months. I'm thinking near end of 2021 or thereabouts, hopefully I get proven wrong.
I'm at risk, but not with particular co-morbidity factors. I'm hoping by March or April, possibly sooner. I wonder if I'll have a choice between the Moderna or Pfizer vaccines. I'd sooner take the Moderna if for no other reason than the apparent fact that requiring much more intense refrigeration would suggest that getting the Pfizer vaccine would introduce some extra uncertainty.
 

ondma

Platinum Member
Mar 18, 2018
2,771
1,351
136
Looks promising for both. Only reservation is that usually we wait for longer term safety information. In this case though, I would definitely take either and live with the possible (very minimal most likely) risks.
 

Fenixgoon

Lifer
Jun 30, 2003
31,808
10,343
136
Given the likely constrained amount of doses thru the middle-ish of next year both vaccines are going to be widely used, just in different settings.

yeah, even the location of the production facilities will play a role in distribution due to the storage/transport requirements.
 

ondma

Platinum Member
Mar 18, 2018
2,771
1,351
136
Well, I am going to give Trump the benefit of the doubt in a couple of areas. It is impossible to say if someone else would have started the lockdown earlier/more effectively. I will also give him credit for pushing a vaccine.

What in my mind is totally unforgivable though, is the way he undermined the prevention efforts from, say mid March till now, most notably undermining mask wearing and subverting governors and local officials in their efforts to contain the spread. Even his attempts to open up the economy were somewhat understandable, but it was unforgivable to not encourage stronger safety measures while doing so.
 

nOOky

Platinum Member
Aug 17, 2004
2,892
1,910
136
Good news. If I were Pfizer's CEO I would have cashed out my stock right when I knew a better vaccine from a competitor was coming out a few days later since there's might get eclipsed by the Moderna verson.
 

brycejones

Lifer
Oct 18, 2005
26,665
24,968
136
Good news. If I were Pfizer's CEO I would have cashed out my stock right when I knew a better vaccine from a competitor was coming out a few days later since there's might get eclipsed by the Moderna verson.
You mean the 5.6m worth he sold the day of the announcement?
 

Commodus

Diamond Member
Oct 9, 2004
9,215
6,818
136
Looks promising for both. Only reservation is that usually we wait for longer term safety information. In this case though, I would definitely take either and live with the possible (very minimal most likely) risks.

Same. As I like to put it: the moment I have access to a vaccine, I'm lining up for it like it's an iPhone launch. It'll be worthwhile even if I still have to wear a mask to be on the safe side.
 

ondma

Platinum Member
Mar 18, 2018
2,771
1,351
136
Good news. If I were Pfizer's CEO I would have cashed out my stock right when I knew a better vaccine from a competitor was coming out a few days later since there's might get eclipsed by the Moderna verson.
Well, I think we will be able to use all they can produce from both companies for the first few months.
I do wonder though, whether we will know which vaccine we are getting or if we will have a choice between the two.
 

Thump553

Lifer
Jun 2, 2000
12,726
2,501
126
If both require two shots (and especially with different schedules, 21 days for Pfizer and 28 for Moderna) both you and your doctor better make sure which vaccine you are on. I imagine one shot of one and the second shot from the other manufacturer is useless or nearly so.
 
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