Yeah, I'll take 99. I've heard of N99 masks, but I only have N95 that at low densities, they aren't as efficient at conquering their hosts. 99 1/2 just won't do:
Yeah, I'll take 99. I've heard of N99 masks, but I only have N95 that at low densities, they aren't as efficient at conquering their hosts. 99 1/2 just won't do:lots of new science starts with accidental something. The other vaccination producers are surely trying the same right now... imagine 95 going to 99.
Without the data and the potentially small sample size of the mistaken dosage group, I think people are jumping the gun on the meaning of the AZ results.lots of new science starts with accidental something. The other vaccination producers are surely trying the same right now... imagine 95 going to 99.
I think jumping the gun would be to shoot up... now they are verifying the finding..... right? right?Without the data and the potentially small sample size of the mistaken dosage group, I think people are jumping the gun on the meaning of the AZ results.
(I apologize in advance if this sounds a little rambling. I'm still waking up, lol)I think jumping the gun would be to shoot up... now they are verifying the finding..... right? right?
Of course not, at least, as a layman, i’d expect them to go through phase 3 again.(I apologize in advance if this sounds a little rambling. I'm still waking up, lol)
It really only sounds like they released a very, very top-line summary of some first interpret-able results. It's really nothing to write home about or draw sweeping conclusions because we simply have nothing to look at. Let's calm down and wait for the full data to come out publicly. These trials generate loads of data that need to be analyzed by statisticians, while they also package the data for regulatory submission.
At the end of the day, the main pieces of data to look at will be the primary endpoint within the entire population, then look at how efficacy might have varied across stratification groups (they'll often stratify the trial by geographic region and one or two other factors, to look for consistency in these key groups), then look at safety across the trial. These subgroup analyses, which is effectively what this half-dose group is, are just interesting hypothesis-generating items or confirmatory for the primary endpoint. These trials are likely not powered to draw statistically meaningful conclusions from small subgroups. And we definitely cannot draw any meaningful conclusions from post hoc analyses of clinical trial data (as that really amounts to statistical fishing).
We are supposed to be getting it around mid December. They are going to inoculate the entire patient facing staff in no particular order.
They probably won't have to run another Phase 3 trial, unless they wanted to explore any new hypotheses, like half dose + full dose vs 2x full dose. I would bet they have enough data to carry them through regulatory approval at the original proposed dose schedule.Of course not, at least, as a layman, i’d expect them to go through phase 3 again.
They probably won't have to run another Phase 3 trial, unless they wanted to explore any new hypotheses, like half dose + full dose vs 2x full dose. I would bet they have enough data to carry them through regulatory approval at the original proposed dose schedule.
Vaccine for what? Creating autism?Estimated 1 billion doses possibly available in 2021. Heard about it today on NPR. Their trial had 90 cases in the placebo group and 5 that got the vaccine, translates to almost 95% effective. Said to be especially effective for the elderly.
Moderna's coronavirus vaccine is 94.5% effective, according to company data | CNN
The Moderna vaccine is 94.5% effective against coronavirus, according to early data released Monday by the company, making it the second vaccine in the United States to have a stunningly high success rate.www.cnn.com
Stays fresh without intense refrigeration unlike the Pfizer vaccine.
Suit yourself. I'll take my chances with the vaccine.Vaccine for what? Creating autism?
Family to Receive $1.5M+ in First-Ever Vaccine-Autism Court Award - CBS News
Number of completed long term tests
Zero
Vaccine for what? Creating autism?
Family to Receive $1.5M+ in First-Ever Vaccine-Autism Court Award - CBS News
Number of completed long term tests
Zero
This is a troll who just joined today, made two posts in the motherboards and windows forums that shows he is obviously not a computer enthusiast then came directly to the politics and news forum to shitpost mindless pro-trump conspiracy and anti-vax garbage.
Vaccines are safer than you operating a computer.Vaccine for what? Creating autism?
Family to Receive $1.5M+ in First-Ever Vaccine-Autism Court Award - CBS News
Number of completed long term tests
Zero
From what I've read, the leading hypothesis on the Oxford vaccine is that because it is a viral vector vaccine, the body produces a stronger response to the vector with the larger first dose and then neutralizes the booster shot without getting a benefit from it. I don't think mRNA would have the same mechanism at all.lots of new science starts with accidental something. The other vaccination producers are surely trying the same right now... imagine 95 going to 99.