I hear you,
@Markfw , and understand the question quite well. I say this reluctantly, but also, what advances do we see from other projects? How can Milkyway NOT have mapped the galaxy by now? They haven't updated results for years. How can the many medical projects have not directly created some sort of a cure for SOMETHING?
I guess stepping stones is the answer, one step into the unknown at a time. It can be frustrating though. We (BOINC) have 10 to 20 x the power of most any corporation, and yet they come up with the vaccine. Not F@H, not Rosetta, not QuChemPedia, not SiDock, not any BOINC project. I will say I am speaking out of my hind side right now, no research done to support my spouting off. Perhaps some open-source info (developed by BOINC'ers), was used in some treatment/cure somewhere? I sure hope so.