The "Deep South" is typically Mississippi, Arkansas, LA, most of Georgia, Alabama, Florida panhandle, probably SC or at least parts of it. It isn't necessarily the same as western NC...though as an NC native, I can assure you that my home state has sure gone to utter shit in recent years, trying to emulate the bronze aged dumbassery of the rest of much of the south with their new draconian laws. But, outside of Georgia and Florida, I daresay most of those states would have real trouble surviving without the north or the Feds. Those are federal welfare states.
You'd be wrong assuming a lack of economical viability.
We have manufacturing all over the place.
We produce a lot of food. I do the grocery shopping for my family. All the produce I purchase is local. However, during Winter months some comes from South America (Peru mostly). The proteins are all from the SE. (I suppose if I ate guacamole I would buy Mexican, or nuts (other than peanuts) I would buy CA produce.)
The so-called 'welfare' is partially or primarily the result of so many Yankees retiring here. They all draw SS and Medicare. Most states in the SE don't have expansive and expensive Medicaid, so they use less federal money for that.
Some SE states have a lot of military contractors receiving DoD money (some count that cash flow as 'welfare'). The ones I personally know design and build robots for the military.
From driving around the country several times over the years the only real difference I see in rural areas is that we have pockets (gated developments with golf courses) of wealthy retirees (from up North/Midwest) and rural areas in the North generally don't. Oh, the other diff is our weather here isn't as harsh in the Winter and our mosquitoes aren't as large.
Upstate NY or the UP in Mich? I don't see a whole hell of a lot of diff.
Fern