Criticality? It sort of depends on what you're doing, and what you need.
I approach criticality from the business perspective: What is the impact ($$, lost business, damage to reputation,inability to complete mission, etc.) on the company if a particular application (functionality) is not available? What's the impact if the application is not available for: 1 hour, 2 hours, 8 hours, 1 day, 1 week?
If it's the application has different levels of availability (limited functionality), ask the same questions as above.
More details?
--Woodie