Scientists create embryo of an extinct species

Page 2 - Seeking answers? Join the AnandTech community: where nearly half-a-million members share solutions and discuss the latest tech.

Ventanni

Golden Member
Jul 25, 2011
1,432
142
106
One of these days, scientists will figure out a way to both write and express genes in the way they want. We'll create monsters, woohoo!
 

diesbudt

Diamond Member
Jun 1, 2012
3,393
0
0
problem is that the DNA is horribly degraded, pretty much beyond use. You can't sequence what isn't there.

Jurassic Park was rather cool in a way, in that it was based on active research at the time, the theory of which was rather sound. It was only discovered that the DNA that was actually extracted was completely useless. Dinosaurs are just too damn old.

It's ok. I got this.

I will build a time machine, wit ha few huge syringes. Jump back in time. Coerce a Velociraptor into a box (much like a cat) by leaving a few boxes out. When they finally come into the box to sit, because lets be honest all animals love sitting in boxes (especially cats). I will walk up to it, jab a few syringes into it and get DNA the old fasion way. Teh run like hell back into my time machines.
 

skillyho

Golden Member
Nov 6, 2005
1,337
0
76
It's ok. I got this.

I will build a time machine, wit ha few huge syringes. Jump back in time. Coerce a Velociraptor into a box (much like a cat) by leaving a few boxes out. When they finally come into the box to sit, because lets be honest all animals love sitting in boxes (especially cats). I will walk up to it, jab a few syringes into it and get DNA the old fasion way. Teh run like hell back into my time machines.

LOL!
 

JTsyo

Lifer
Nov 18, 2007
11,774
919
126
They couldn't survive here anyway. There's not enough oxygen in the air now to support them.

yea, that plus the lower air pressure might be tough for them. The O2 was high enough that they could get more O2 per breath to support their size.

Thought I read a while back that smaller animals didn't even need lungs at that point but I can't find any links to confirm that.
 

GagHalfrunt

Lifer
Apr 19, 2001
25,297
2,001
126
problem is that the DNA is horribly degraded, pretty much beyond use. You can't sequence what isn't there.

The $64,000 question is whether the DNA is completely gone or simply degraded beyond the point where current technology can read the information. It wasn't that long ago that being able to sequence DNA of any age would have been impossible, it's possible that the information is there and beyond our capabilities to see it. As improved telescopes unlocked places in the universe once out of view it's not too hard to believe that advances in DNA tech will someday make it possible to see what we can't see now.
 

zinfamous

No Lifer
Jul 12, 2006
110,819
29,570
146
The $64,000 question is whether the DNA is completely gone or simply degraded beyond the point where current technology can read the information. It wasn't that long ago that being able to sequence DNA of any age would have been impossible, it's possible that the information is there and beyond our capabilities to see it. As improved telescopes unlocked places in the universe once out of view it's not too hard to believe that advances in DNA tech will someday make it possible to see what we can't see now.

it would involve lots of inference, as basically what you have with extracted dino DNA, is an assembly (such as it is; no one has ever attempted a true dino assembly, afaik) that is full of massive holes, and the base calls that you do have, probably have low confidence.

If we have complete assemblies of critters like crocodiles and alligators and sharks and various moniter lizards, we could theoretically approach something like a complete dinosaur assembly. So--much like with jurassic park, you would be using closely-related ancestors to plug in massive gaps, ....but these are huge gaps. And this is for assembly purposes, so mostly working out of theory and no practical or reasonable ability to generate a critter from such knowledge. (We can kinda sorta now make a single-celled organism from synthetic RNA; but actually making a dinosaur, outside of somatic cell nuclear transformation? hmmm)
 

GagHalfrunt

Lifer
Apr 19, 2001
25,297
2,001
126
it would involve lots of inference, as basically what you have with extracted dino DNA, is an assembly (such as it is; no one has ever attempted a true dino assembly, afaik) that is full of massive holes, and the base calls that you do have, probably have low confidence.

If we have complete assemblies of critters like crocodiles and alligators and sharks and various moniter lizards, we could theoretically approach something like a complete dinosaur assembly. So--much like with jurassic park, you would be using closely-related ancestors to plug in massive gaps, ....but these are huge gaps. And this is for assembly purposes, so mostly working out of theory and no practical or reasonable ability to generate a critter from such knowledge. (We can kinda sorta now make a single-celled organism from synthetic RNA; but actually making a dinosaur, outside of somatic cell nuclear transformation? hmmm)

WHOOSH!

Once again, the $64,000 question is how you're so sure about those gaps. Is the information truly missing or are we missing it because the current tech isn't up to the job? This is a science in its infancy, there's a lot left to learn both with the DNA and with the tools used to read the DNA. Science could be sitting on a complete strand of dinosaur DNA and not even know it because the tech can't see it YET.
 

randomrogue

Diamond Member
Jan 15, 2011
5,462
0
0
The word impossible is something I tend to avoid in conversations about this since I know jack shit and the science is relatively new. What were people saying about cloning 50 years ago? Didn't they say that human cloning was impossible but then they changed their mind?
 

adairusmc

Diamond Member
Jul 24, 2006
7,095
78
91
It's ok. I got this.

I will build a time machine, wit ha few huge syringes. Jump back in time. Coerce a Velociraptor into a box (much like a cat) by leaving a few boxes out. When they finally come into the box to sit, because lets be honest all animals love sitting in boxes (especially cats). I will walk up to it, jab a few syringes into it and get DNA the old fasion way. Teh run like hell back into my time machines.

 

zinfamous

No Lifer
Jul 12, 2006
110,819
29,570
146
WHOOSH!

Once again, the $64,000 question is how you're so sure about those gaps. Is the information truly missing or are we missing it because the current tech isn't up to the job? This is a science in its infancy, there's a lot left to learn both with the DNA and with the tools used to read the DNA. Science could be sitting on a complete strand of dinosaur DNA and not even know it because the tech can't see it YET.

um, yeah. We pretty much know what we can and can't see. We know it isn't there, because it...isn't there.

The only way to improve this is to discover yet a new "magic" (highly robust) type of polymerase that can further synthesize the crappy samples that we have access to--meaning, longer strands of nucleotides that will be just as crappy as what we can now do...just longer.

so in terms of your line of questioning, I would lean more towards "current tech isn't up to the job, with the highly unlikely potential that it ever will be."

starting with RNA, you can do funny things like 5' RACE (there is an equivalent method using DNA--I forgot what it is called), what will allow you to sequence --very short regions--into 5' ends that are unknown. Good luck finding some dino RNA, RNA. But maybe something like this could be applied using DNA.
 

zinfamous

No Lifer
Jul 12, 2006
110,819
29,570
146
The word impossible is something I tend to avoid in conversations about this since I know jack shit and the science is relatively new. What were people saying about cloning 50 years ago? Didn't they say that human cloning was impossible but then they changed their mind?

for this debate, the impossibility of human cloning is mostly related to an ethical argument, more than an argument regarding biological possibility.
 

CZroe

Lifer
Jun 24, 2001
24,195
856
126
The word impossible is something I tend to avoid in conversations about this since I know jack shit and the science is relatively new. What were people saying about cloning 50 years ago? Didn't they say that human cloning was impossible but then they changed their mind?
What? No one said human cloning was impossible. That's particularly why it remained in sci-fi from moments after DNA was discovered all the way until now. Hell, my teacher used it as an example when describing what DNA was when I was first learning about it decades ago.
 

IGBT

Lifer
Jul 16, 2001
17,956
137
106
I'm sure they are working furiously to bring ted kennedy back to life.
 

Agent11

Diamond Member
Jan 22, 2006
3,535
1
0
Personally I think Human cloning should be allowed. Who's to tell me it is wrong to clone myself and raise me as my son.
 

Craig234

Lifer
May 1, 2006
38,548
349
126
It'd be great to bring back species, but you should care more about preserving the ones we have, which we are losing at an enourmous rate.

Not many know that in the history of the planet there have been six maxx extinction events, and the sixth is currently occuring.

Donate to "Center for Biological Diversity" or your nearest progressive politician.
 

randomrogue

Diamond Member
Jan 15, 2011
5,462
0
0
It'd be great to bring back species, but you should care more about preserving the ones we have, which we are losing at an enourmous rate.

Not many know that in the history of the planet there have been six maxx extinction events, and the sixth is currently occuring.

Donate to "Center for Biological Diversity" or your nearest progressive politician.

Within our lifetimes we might lose the Rhino, Tiger, Orangutan, Gorilla, Chimpanzee, Nile Crocodile, Giant Panda, North Atlantic Bluefin Tuna, Blue whale, Sperm Whale, a bunch of dolphins like the Irrawaddy, and god knows how many other large species.
 
sale-70-410-exam    | Exam-200-125-pdf    | we-sale-70-410-exam    | hot-sale-70-410-exam    | Latest-exam-700-603-Dumps    | Dumps-98-363-exams-date    | Certs-200-125-date    | Dumps-300-075-exams-date    | hot-sale-book-C8010-726-book    | Hot-Sale-200-310-Exam    | Exam-Description-200-310-dumps?    | hot-sale-book-200-125-book    | Latest-Updated-300-209-Exam    | Dumps-210-260-exams-date    | Download-200-125-Exam-PDF    | Exam-Description-300-101-dumps    | Certs-300-101-date    | Hot-Sale-300-075-Exam    | Latest-exam-200-125-Dumps    | Exam-Description-200-125-dumps    | Latest-Updated-300-075-Exam    | hot-sale-book-210-260-book    | Dumps-200-901-exams-date    | Certs-200-901-date    | Latest-exam-1Z0-062-Dumps    | Hot-Sale-1Z0-062-Exam    | Certs-CSSLP-date    | 100%-Pass-70-383-Exams    | Latest-JN0-360-real-exam-questions    | 100%-Pass-4A0-100-Real-Exam-Questions    | Dumps-300-135-exams-date    | Passed-200-105-Tech-Exams    | Latest-Updated-200-310-Exam    | Download-300-070-Exam-PDF    | Hot-Sale-JN0-360-Exam    | 100%-Pass-JN0-360-Exams    | 100%-Pass-JN0-360-Real-Exam-Questions    | Dumps-JN0-360-exams-date    | Exam-Description-1Z0-876-dumps    | Latest-exam-1Z0-876-Dumps    | Dumps-HPE0-Y53-exams-date    | 2017-Latest-HPE0-Y53-Exam    | 100%-Pass-HPE0-Y53-Real-Exam-Questions    | Pass-4A0-100-Exam    | Latest-4A0-100-Questions    | Dumps-98-365-exams-date    | 2017-Latest-98-365-Exam    | 100%-Pass-VCS-254-Exams    | 2017-Latest-VCS-273-Exam    | Dumps-200-355-exams-date    | 2017-Latest-300-320-Exam    | Pass-300-101-Exam    | 100%-Pass-300-115-Exams    |
http://www.portvapes.co.uk/    | http://www.portvapes.co.uk/    |