I played another hour earlier this afternoon and decided to just throw shit down wherever and not really have any kind of plan, mainly to see what would happen. I ran into some interesting, albeit not unexpected results.
Since the wind speed and direction is always the same in this plot for the beta test, I decided to throw all my industrial in the upper corner, downwind and away from the beach. I put only one road out there and then kinda forgot about it until much later. I sat there and watched it for a bit and the traffic jam was endless.
http://i.imgur.com/ePCWBJd.jpg
I added an extra road just to see if any cars would take the long way around to avoid the traffic jam. Answer is:
http://i.imgur.com/ea9f8qo.jpg
I ended up turning speed to cheetah and just throwing down as much as I could. Roads wherever, residential where it would fit, hospitals, schools, extra power, etc. Just throwing money at it, since I was actually doing pretty good early on. However, things started going badly, as industrial slowed down, people didn't have jobs, crime increased, people were getting sick (partly because I accidentally left my lone water tower near my industrial zone and they were polluting the water table).
http://i.imgur.com/b5eTzUV.jpg
I could zoom in and hear gun shots ringing out quite often. Blocks of residential weren't getting built, commercial projects were sitting untouched, I was losing $2k an hour not too long after that screenshot was taken. You definitely can't wing it in this game, you have to have some type of plan and take it slow, unless you're a Sim City pro (which I am not).
Really loving this game, can't wait to play with others.