I have one. I've got my P3-650 running at 866 1.65v, which is pretty good, that was what I was hoping for.
The good:
-I just dumped all my PCI cards in and they worked. SB Live, Hauppauge WinTV Theater, Sigma Designs Hollywood+ DVD card, 3Com 2977 OEM v.90 PCI modem, and an Intel Pro/100+ Management adapter. Plus a CL Annihilator 2.
-The board is super stable. No hardware crashes, some software/driver problems with my abCD CDrw proggie and IE 5.5 + active desktop (no idea why).
-Live Andy Hui, I have been staring at that Asus iPanel connector and am currently looking for an Asus iPanel. Could be fun messing with that thing.
-The 5 USB ports are nice.
The bad:
-For some reason, my CPU temp monitoring is screwed. My CPU, according to the BIOS/Asus Probe, is running at a chilly 8 deg C and my motherboard is at 25 deg C. I don't think my Alpha FC-PAL35 is THAT effective. My friend also has the same problem but both of our boards came from the same batch/box so it could be just us. Asus boards usually, from what I've seen, have temperature monitoring problems for the first couple of BIOSes.
Needless to say, the good totally outweighs the bad. This board is probably the easiest to install, and the most stable I have ever used. That a pretty big thing to say considering I only use Asus motherboards.
Btw, if you guys are going to get the CUSL2, I suggest you download the latest i815E chipset utility off of Intel's site (not sure if the one on the CD is the latest) and Asus forgot to include the Intel Ultra ATA Storage driver on the CD so you are going to want to download that too.