Son of a b, Tamiflu is expensive.

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Lifer
Sep 26, 2000
28,561
4
0
How many billions in R&D did Roche and Gilead spend on other drugs that never made to market?

Yeah, but what about all the drugs they push for diseases they are not approved for?
And how about all the government funded R&D that the drug companies get from the taxpayers?
Or how about how they have a loophole in the law that lets them double the patent?
 

Hayabusa Rider

Admin Emeritus & Elite Member
Jan 26, 2000
50,879
4,266
126
I don't know if there is a good source of that information. But, we can guess. Gilead Sciences had a $86M IPO warchest in 1992. Four years later, Tamiflu was patented along with several other products. Lets just guess on the large side that Tamiflu development required half of thier money. So, $43M to get it patented. At that point Roche bought the rights. I don't know what Roche paid for FDA approval for that drug. But I have dealt with Roche for other products and Roche told me that they typically pay $7M to $10M for each approval. Probably since Tamiflu is a big drug, they paid more for more research. Until someone links real information, I'll just guess $20M. Note: the federal goverment picks up about half of the expenses, so lets add on another $20M. That gives us $43M + $20M + $20M = $83M as a very rough guess. If anyone has concrete numbers, I'll gladly update.

Now, there may have been other expenses. The goverment may have given Gilead grant money to help develop it. The government was also planning to spend $1B to stockpile it (does anyone here know how much was actually spent?). Not coincidently, a nameless goverment employee at the time received tens of millions of dollars in his stock share increase from this announcement. I think the "Tamiflu was expensive to develop" argument is a bit overused. They already got a ~15x return on the non-government expenses.

My bias in case you are wondering: I develop medical tests for a living and my wife works at a well-known pharmaceutical company.


I was about to post the same thing. You must be able to itemize, you must have massive expenses that aren't covered by insurance, and the insurance premiums aren't usually deductable in this category.

Typical cost to bring a new drug to market is half a billion. No that's not with marketing.
 

Hayabusa Rider

Admin Emeritus & Elite Member
Jan 26, 2000
50,879
4,266
126
Yeah, but what about all the drugs they push for diseases they are not approved for?
And how about all the government funded R&D that the drug companies get from the taxpayers?
Or how about how they have a loophole in the law that lets them double the patent?


How about half billion dollar drugs that only a few thousand people are going to use?

To be sure drug companies are profitable, but the idea that you can turn hundreds of millions into billions with everything they touch isn't reality.
 

Fritzo

Lifer
Jan 3, 2001
41,892
2,135
126
I had to get 4 doeses of it, and after insurance it was still $85 a pop :|, so $340 for the family a month before Christmas.

Yeah Obama! Keep your hands off my healthcare! It works great!!!!
 

PlasmaBomb

Lifer
Nov 19, 2004
11,815
2
81
How many billions in R&D did Roche and Gilead spend on other drugs that never made to market?

In 1999, PhRMA testified that the average cost of drug development was $0.5 billion, and that only 1 in 5,000 compounds are successful.

Bristol-Myers Squibb now claims that it has spent more than $1
billion to develop Taxol, a drug it did not invent.
MSF Working Group on R&D, 2000

Drugs cost money, mmmmkay?
 

Gibsons

Lifer
Aug 14, 2001
12,530
35
91
I thought it was 5 billion to bring a new drug to market

Some might be... It depends on a lot of things. Sometimes research just takes a while. Some clinical trials are much much more expensive than others.
 

PlasmaBomb

Lifer
Nov 19, 2004
11,815
2
81
Roche generally doesn't do much R&D. They buy companies that have already done the R&D. Roche also spends billions on ads to promote their products. So, Roche spends billions, but NOT on research.

According to their accounts Roche spent $8.7 on R&D in 2008...
~90% of that was on pharmaceuticals.

Fail.
 

dullard

Elite Member
May 21, 2001
25,214
3,627
126
According to their accounts Roche spent $8.7 on R&D in 2008...
~90% of that was on pharmaceuticals.

Fail.
You fail to see the scope of things. $8.7 is just pennies to Roche (even if you really meant $8.7B, that is still pennies).

For example, Roche offered $43.7B for just half of Genentech. http://www.nytimes.com/2008/07/22/business/worldbusiness/22roche.html

On the first Google search page for acquisitions in the last two years, I see that: Roche aquired Ventana for $3.4B, Roche offered $1B for Synta, Roche offered $0.6B for BioVeris, $0.3B for NimbleGen, just last week offered $0.2B for Medingo, $0.05B for Memory, $0.2B for ARIUS, $0.2B for 454 Life Sciences, $0.1B for Mirus, $0.05B for THP, etc. I'm sure there are more if I kept going on to more Google pages.

Roche has also had many other massive deals. Boehringer Mannheim for $11B, Syntex for $5.3B, etc.

Roche does minimal R&D, mostly as finishing up the R&D at companies that it took over. Roche does not really actively try to come up with new drugs itself. Roche is more of an investment firm. It sees potential in a new drug/device built by another company, buys it, and then turns around and charges you a premium for the drug. You are rewarding the investor, not the drug inventor. Yes, you could argue that it indirectly funds drug research since it'll spur on other companies to keep researching in hopes to sell to Roche. But that is the closest link you can really make.
 

bl4ckfl4g

Diamond Member
Feb 13, 2007
3,669
0
0
I have really good insurance but it was still 50 dollar copay. My copays are normally only 10 or 15.
 
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