I'm torn.
Winamp's ease of use is marvelous. Playlist support is generally better, and it's a lot easier to get to whatever song I want.
Sonique sounds much better. However, I do not like things that hang out in my taskbar without my permission. There's no checkbox to disable it.. Even Real Player lets you do that. And it's SLUGGISH at changing songs and jumping to a part of a song. I have a 600mhz PC and it's still a second delay. Winamp was instantaneous. And for whatever reason, Sonique does not play when you preview the file in Napster. Winamp had no problem.
I'll probably switch back to Winamp, but I have to ditch the Nitrane decoder before I do so.
I liked Sonique for a while, but damn, sometimes I just want to listen to some music and it makes it a pain