So...let me ask this...(I hope I word it right) Does the motherboard process/output sound differently for the audio jacks than USB? That's to say, the audio ports use the built-in Realtek ALC 4080 chip and codec...is that still used for USB out to a DAC?
If using SPDIF pass-through it theoretically shouldn't sound differently but that is something only you could decide. If you setup your K5PRO as a USB sound card with DAC, you would need to install a USB DAC (ASIO) driver in order to route the audio stream properly. Then select the USB DAC as your playback or output source, not the Realtek Sound.
Best way to make sure the mobo audio is not being utilized is to disable the onboard Realtek audio, either in BIOS or via Device Manager. Then install your DAC as USB soundcard or DAC.
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