When you have to go all the way back to the civil war, and beyond, to the geological evolution of the planet, to excuse why the southern states are doing so poorly, then you have a problem. I'll grant that you can find a deterministic causal sequence traceable backwards in time to the formation of the universe to explain why any given thing is the way it currently is. But we're getting far afield of the context of this discussion.
The context is this. People on the left bring up the fact that blue states pay the majority of taxes while red states take the majority of services for two related reasons. First, because conservatives incessantly complain about paying taxes which then get spent by the government to benefit the less fortunate. This is tough for liberals to swallow when it's the blue states paying the majority of the taxes while the red states are getting most of the benefits. Liberals don't mind the idea of this at all. In fact, we support it in concept. But when the primary beneficiaries of it do nothing but complain about the idea of this wealth transference, do not expect liberals to sit quiet and not bother to point out the irony and the hypocrisy.
Second, because of the cultural animus that conservatives have toward blue states, you often hear them saying things like they wish California would secede and leave the country. These fools appear to have no idea that 15% of the nation's food supply, including almost half the fruits, vegetables and dairy is grown here, and that the most rapidly expanding US industry, IT, has its nexus here, and it benefits the entire country. The US is starting to lag technologically behind countries like China precisely because modern conservatives oppose using tax dollars the way the Chinese do to maintain our technological edge. But at least we have Silicon Valley, in spite of conservatives, not because of them. Perhaps conservatives shouldn't be maligning something which is such a tremendous benefit to all of us, including them.
The simple fact is that, no matter the distant historical reasons, red states need blue states a lot more than blue states need red states. Perhaps we wouldn't feel the need to rub their noses in this if they didn't hate us so much.