The problem I have with eSATA is that I cannot seem (in Win7 anyway) to plug a drive in and have it pop up in the my computer window. USB works that way and I can "eject" it and unplug it on the fly. I wish eSATA worked that way on Win7 and I've tried everything. It's either plugged in all the time, or I use USB instead.
I don't know what your playing with it.... But I have an external 5 bay enclosure....running eSATA.... with 3 2TB drives in it...I can un plug and plug and plug and play all day....WIN& sees it...then it doesnt....then it does...instantly....