Standard addition is an analytical technique of extreme importance to an analyst, as it eliminates the interfering effect in most determinations. Fluoxetine is widely used as fluoxetine hydrochloride, also known as Prozac®. This is indicated in the treatment of depression, associated or not with anxiety. This compound absorbs ultraviolet light at a wavelength of 227 nm. It has in its structure a stereocenter, being a chiral drug. It is known that only the (R) -fluoxetine isomer has activity, while the other enantiomer has no pharmacological action and there is no evidence of toxicity to the organism.
In an industry, when performing the Fluoxetine analysis, the following analytical calibration curve was obtained, in which the concentration is in g / 100 mL: Abs = 372 CFluoxetine + 0.6432.
Knowing the analysis was performed according to the standard addition technique and that the molar mass of fluoxetine hydrochloride (C17H18F3NO.HCl) is 345.79 g / mol. Determine the mol / L concentration in the analyzed solution.
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admin allisolm
In an industry, when performing the Fluoxetine analysis, the following analytical calibration curve was obtained, in which the concentration is in g / 100 mL: Abs = 372 CFluoxetine + 0.6432.
Knowing the analysis was performed according to the standard addition technique and that the molar mass of fluoxetine hydrochloride (C17H18F3NO.HCl) is 345.79 g / mol. Determine the mol / L concentration in the analyzed solution.
We ask everyone to do their own homework.
admin allisolm
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