The IDE connectors may interfere with some longer cards, but there are also a large number of cards that will fit. However, since there are 6 PCI slots, there shouldn't be too much to worry about.
You would only need to worry about true full-length cards if you have some older PCI cards that you still want to use (like an original SB Live!). Also, unless you have 4 or 5 full length cars, I really do not see any issues with the Epox.