What is going on with the story on ivermectin?

abj13

Golden Member
Jan 27, 2005
1,071
902
136
That is an outdated analysis that includes a study that has been retracted due to scientific flaws (a study that showed the greatest benefit to ivermectin). Other studies that are included are also significantly flawed and has been summarized elsewhere with discussions like this in the Atlantic, Buzzfeed, and others.

Other reviews acknowledge the limited data out there, and don't formulate the same conclusions as the metanalysis you linked to, cautioning against any strong suggestion that Ivermectin does anything:

It went so far that one group even withdrew their metanalysis because it included the retracted paper I mentioned above.
 
Dec 10, 2005
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Don't cherry pick sources just because they are contradictory to consensus or support preconceived notions.

Ivermectin is not an established method to treat COVID, and should be avoided for such used.
 
Reactions: Pohemi and dank69

hal2kilo

Lifer
Feb 24, 2009
23,652
10,515
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Separately, meta study indicated that in selected regions with high prevalence of worms in humans, ivermectin did improve statistical outcomes on COVID - which is a rather logical outcome. (While it has no benefit otherwise).
Now you did it. People are going to start picking up land mines and eating them now. (slang for dog poo).
 

dullard

Elite Member
May 21, 2001
25,214
3,627
126
I have been lead to believe ivermectin is a horse deworming medicine that whack job charlatans push as a cure for Covid. This link suggests a different story:


Any thoughts?
Here is their table #2, with a focus on the Quality of Evidence. This table compares Ivermectin as treatment to no Ivermectin. Then see table 4 for Ivermectin as preventative (hint: all data was either low quality or not reported).
OutcomesQuality of the evidence (GRADE)
Death from any causeModerate†
Recovery time to negative PCR test, in daysVery low†,‡,§
Time to clinical recovery, in days (outpatients)Very low†,‡,§
Time to clinical recovery, in days (mild to moderate COVID-19 inpatients)Very low†,¶
Time to clinical recovery, in days (severe COVID-19 inpatients)Very low†,¶
Admission to ICUVery low¶,║¦
Need for mechanical ventilationLow§,║
Length of hospital stay, in daysVery low†,¶
Admission to hospitalVery low†,¶
Improvement (mild to moderate COVID-19)*Low†,‡
Deterioration (any disease severity)Low†,‡
Serious adverse eventsLow†,‡

Two of the authors have a GoFundMe to get Ivermectin money (Tess Lawrie and Therese Dowswell: https://www.e-bmc.co.uk/ ) No conflict of interest there.

One author faced disciplinary action for refusing to give vaccines and resigned from his post (Scott Mitchell) https://www.bailiwickexpress.com/js...-over-vaccine-questions-lawyers/#.YfL_E57MJhE

Remember, a bullet can prevent Covid infection too. Napalm can cure Covid in a petri dish. Don't focus on the headlines. Look into the data.
 
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Moonbeam

Elite Member
Nov 24, 1999
72,699
6,196
126
How about you?

Am simply fascinated by what seems like grasping at straws appears to be taken so seriously. I find it provocatively interesting in trying to reach any level of certainty on matters that are quite serious, and have political ramifications, how seemingly muddled so many of them seem to become.

As someone, in my opinion, at least, long resigned to the supposition we are fucked, I find myself neither interested in or reject I’ve of end time scenarios for lack of better word. But I am curious about what is going on in people’s heads.

if I wanted to get conspiratorial myself, I might suggest there is a big effort being made behind the scenes to discredit any sense of credibility or authority, and here specifically, that science itself might have.

Like economists, scientists are looking more and more to be speaking with two hands. There is no such thing as a straight answer.

I thing that might well imply some sort of psychological motivation from which a market for distortion will arise.

If I were to go down that rabbit hole I would put the following on a list of suspects. The Chinese, the Russians, religion, the Republican Party, and industries with bottom lines threatened by facts or sales threatened by intelligent thinking.
 

dank69

Lifer
Oct 6, 2009
35,596
29,300
136

Am simply fascinated by what seems like grasping at straws appears to be taken so seriously. I find it provocatively interesting in trying to reach any level of certainty on matters that are quite serious, and have political ramifications, how seemingly muddled so many of them seem to become.

As someone, in my opinion, at least, long resigned to the supposition we are fucked, I find myself neither interested in or reject I’ve of end time scenarios for lack of better word. But I am curious about what is going on in people’s heads.

if I wanted to get conspiratorial myself, I might suggest there is a big effort being made behind the scenes to discredit any sense of credibility or authority, and here specifically, that science itself might have.

Like economists, scientists are looking more and more to be speaking with two hands. There is no such thing as a straight answer.

I thing that might well imply some sort of psychological motivation from which a market for distortion will arise.

If I were to go down that rabbit hole I would put the following on a list of suspects. The Chinese, the Russians, religion, the Republican Party, and industries with bottom lines threatened by facts or sales threatened by intelligent thinking.
Yes, there is a concerted effort to discredit scientific consensus. That isn't conspiratorial, that has happened and continues to happen despite the perpetrators being caught red-handed many many times over the past few decades. It happened with lead. It happened with cigarettes, It happened with global warming and it is happening again with the pandemic. The fact that you would say "Like economists, scientists are looking more and more to be speaking with two hands. There is no such thing as a straight answer" just shows that their efforts are working on you.
 

desy

Diamond Member
Jan 13, 2000
5,438
211
106
Am simply fascinated by what seems like grasping at straws appears to be taken so seriously. I find it provocatively interesting in trying to reach any level of certainty on matters that are quite serious, and have political ramifications, how seemingly muddled so many of them seem to become.

It started in countries with NO vaccine access, when you have a desperate population grasping for hope they prescribe panaceas.. Then AV unwilling to take a ounce of prevention looking for the pound of cure it seems, glom onto third world country medicine to rationalize choices. . .
Its only sad when they come up against the truth of it and find their indifference or willful ignorance leaves them with health consequences go fund me and orphaned children.
 

Jaskalas

Lifer
Jun 23, 2004
33,574
7,637
136
Yes, there is a concerted effort to discredit scientific consensus. That isn't conspiratorial, that has happened and continues to happen despite the perpetrators being caught red-handed many many times over the past few decades. It happened with lead. It happened with cigarettes, It happened with global warming and it is happening again with the pandemic. The fact that you would say "Like economists, scientists are looking more and more to be speaking with two hands. There is no such thing as a straight answer" just shows that their efforts are working on you.

Largely agree, though the focus on "you" in unwarranted. It works on a great many people and has gone so far as to make us appreciate that our two political parties operate on two entirely separate sets of facts. Rendering any mutual understanding impossible. We, as a nation, are rendered utterly dysfunctional as a result of this disease. This attack on our belief in science. At this point it has almost destroyed us.
 

Moonbeam

Elite Member
Nov 24, 1999
72,699
6,196
126
How about you?
PS: Gorski?, the guy in the second link, didn’t want to have to deal with what he feels was just old bullshit shined up, but he did. There is also the issue of exhaustion. This guy stayed rational. Appreciate @dullard above for that.
 

interchange

Diamond Member
Oct 10, 1999
8,022
2,872
136
The reality is more complicated than politics captures and the average lay person has the capacity to analyze.

As stated above, there is literature in favor of it as a treatment, and the quality of that data is low. Unlike the initial fuss of hydroxychloroquine, ivermectin started being pushed when outcomes of treating COVID were getting much better, and established treatments came along. It is certainly reasonable to study with higher quality randomized controlled trials, but it is far from established as a treatment for COVID.
 

brandonbull

Diamond Member
May 3, 2005
6,330
1,203
126
You're still searching for a way to justify your belief in snake oil.
It will be Interesting what the results of the research from Duke University turn out to be.

 

dank69

Lifer
Oct 6, 2009
35,596
29,300
136
It will be Interesting what the results of the research from Duke University turn out to be.

It will be interesting to watch you ignore the results should they not go your way.
 

Moonbeam

Elite Member
Nov 24, 1999
72,699
6,196
126
The verifiable experiments that validates reality, every single time.
I mean I could forego all that and just jump on the jew space lasers train… If the sex goes up with the crazy theres alot of fun to be had on that side… hmmmm
For a very long time experimental observations of the orbit of Mercury validated Newtonian mechanics. Then for a while they couldn’t be explained. Re-evaluation had to take place. In situations of questioning and flux, there are those who come up with absurd ideas and people whose reputations or ideological suppositions are wedded to the old way of thinking. Truth will most likely appeared to those not attached emotionally to any one thing but seek factual data to back up even ideas that at first may seem ridiculous. Personally I think the number of folk who are essentially emotionally open to going toward or away from accepted wisdom is far less than those who imagine they are like that. I am a believer that bias can easily infect high places.
 

fskimospy

Elite Member
Mar 10, 2006
84,812
49,498
136
For a very long time experimental observations of the orbit of Mercury validated Newtonian mechanics. Then for a while they couldn’t be explained. Re-evaluation had to take place. In situations of questioning and flux, there are those who come up with absurd ideas and people whose reputations or ideological suppositions are wedded to the old way of thinking. Truth will most likely appeared to those not attached emotionally to any one thing but seek factual data to back up even ideas that at first may seem ridiculous. Personally I think the number of folk who are essentially emotionally open to going toward or away from accepted wisdom is far less than those who imagine they are like that. I am a believer that bias can easily infect high places.
But why would there be bias? Is the idea that the $200 billion mega corporation that would be sitting on a gold mine if ivermectin were effective decided it wasn’t because it was wedded to conventional wisdom or hated Trump or something?

It’s always important to ask yourself these questions.
 
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